Tocotrienol ntụ ntụ

Aha ngwaahịa: Tocotrienol
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Gịnị bụ tocotrienol ntụ ntụ?

Tocotrienol ntụ ntụ bụ onye otu ezinụlọ vitamin E ma nwee mmetụta antioxidant. A na-ekewa vitamin E na okike n'ime ezinụlọ abụọ bụ isi, otu bụ Tocopherol na nke ọzọ bụ Tocotrienol. Ihe dị iche n'etiti ha abụọ dị na nhazi ha. Tocopherols bụ sịntetik; tocotrienols bụ ihe okike. Nke kachasị mkpa, tocotrienols nwekwara mmetụta antioxidant siri ike, na-eweta uru ahụike ka ukwuu.

Uru Tocotrienol

A maara Vitamin E maka njirimara antioxidant ya, nke na-enyere aka ịkwụsị radicals n'efu n'ime ahụ. Kpọmkwem, tocotrienols na-akwado ahụike obi, ọkwa cholesterol dị mma, na ọbụna ahụike eriri afọ. E gosikwara na ọ na-akwado ahụike uche, ahụike ọkpụkpụ, ntutu isi na ahụike ntu.

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Akụkọ ihe mere eme na nchọpụta nke tocotrienols

Ọ bụ ezie na a chọtara vitamin E (ụdị alfa-tocopherol) n'oge dị ka afọ 1920, ọ bụ na 1960 ka a na-enyocha tocotrienols wee kpebie na ọ ga-abụ akụkụ nke osisi ezinụlọ vitamin E. A na-akpọ vitamin E "vitamin" n'ihi na ọ dị mkpa maka ịmụ nwa na mgbe ụfọdụ a na-akpọ ya "vitamin ọmụmụ." Achọpụtara ọrụ antioxidant ya na mbụ (1930s). Dr. Barrie Tan, onye chepụtara ọtụtụ usoro maka ịwepụta tocotrienols sitere na isi mmalite, mepụtara tocotrienols site na isi mmalite dị ugbu a (osikapa, nkwụ na annatto) Onye mbụ. Nchọpụta ndị a gụnyere tocotrienols sitere na mmanụ nkwụ (1992), osikapa japonica (1998), na annatto (2002).

Gịnị bụ uru nke tocotrienols?

belata cholesterol. Ọgwụ ọgbara ọhụrụ na-egosi na sterol karịrị akarị bụ otu n'ime ihe na-ebute ọrịa obi, ọkachasị ọkwa dị elu nke lipoprotein dị obere, bụ ihe dị mkpa na-akpata ma bụrụkwa isi ihe na-ebuga cholesterol n'anụ ahụ. N'ime nnwale imeju mmadụ, tocotrienol na-egbochi ọrụ HMG-CoA reductase (hydroxymethylglutarate coenzyme A reductase) nke na-eme ka cholesterol biosynthesis n'ime imeju site na usoro nchịkwa post-transcriptional, si otú ahụ na-ebelata LDL nke ọma na serum -Cholesterol na mkpokọta cholesterol, mkpokọta cholesterol. synthesis belatara site na 32%. Tocopherol enweghị ọrụ na-egbochi enzyme.

Na-akwalite mmepe neuron. Nnwale ejiri teknụzụ mgbawa mkpụrụ ndụ ihe mụọ mmetụta vitamin E nwere na mmepe ụbụrụ nwa ebu n'afọ na oke. Nsonaazụ gosiri na ọkwa α-tocopherol na ụbụrụ nwa ebu n'afọ bụ ihe dịka 1/2 nke nne. N'ime otu tocotrienol-agbakwunyere, ọkwa α-tocopherol na ụbụrụ nwa ebu n'afọ dị ala karịa nke nne. -Ọkwa tocotrienol dị elu nke ukwuu karịa nke nne, na-egosi na tocotrienols na-enwekarị ike imebi ihe mgbochi ụbụrụ ọbara. Tụkwasị na nke ahụ, α-tocotrienol nwekwara ike igbochi mmeghachi omume ntụgharị mgbaàmà nke glutamate kpatara nke na-eduga na neurodegeneration n'ime ahụ, nke bụ ọrụ nke tocopherol enweghị.

Na-akwalite ahụ ike nkwonkwo. N'ikwu okwu n'ozuzu, vitamin D nwere njikọ chiri anya na ọkpụkpụ na nkwonkwo, nyocha ndị na-adịbeghị anya egosiwo na vitamin E na-ekerekwa òkè dị mkpa na ahụike ọkpụkpụ. Nnwale a na-ahụ anya, nke kpuru ìsì abụọ, ebe a na-achịkwa ebebo na-ebipụta na akwụkwọ akụkọ Nutrition sochiri ụmụ nwanyị 87 postmenopausal (nkezi afọ 60) na-adị ala karịa nkezi ọkpụkpụ maka izu iri na abụọ. Nsonaazụ na-egosi na mgbakwunye nke tocotrienol na-eme ka ọkpụkpụ ọkpụkpụ dịkwuo mma ma bụrụ nhọrọ ọhụrụ dị mma ma dị irè maka nlekọta ahụike ọkpụkpụ.

Mmetụta anti-oxidize. Dị ka antioxidant na-agbaze abụba, tocopherol na-adịkarị na akpụkpọ anụ sel, na-ejide radicals free nke sitere na lipid oxidation na-arụ ọrụ ụfọdụ antioxidant. Nnyocha sayensị achọpụtala na ngwakọta agwakọta nke nwere alfa-tocotrienol nke ewepụtara na mmanụ nkwụ bụ ihe antioxidant ka mma. Ọrụ antioxidant ya bụ ugboro 40 ruo 60 karịa nke alfa-tocopherol, enwere ike iwepụ ya nke ọma. Radikal efu na membranes cell lipid, si otú a na-egbu oge ịka nká.

Gbochie atherosclerosis. Nnyocha sayensị achọpụtala na tocotrienols nwere ike igbochi mmeghachi omume peroxidation nke lipids cell membrane, na-abawanye ikike antioxidant nke lipoprotein dị obere (LDL), belata mmepụta nke lipoprotein dị elu (HDL), ma chebe lipoprotein dị ala (LDL). . Echebere na oxidation. Tocotrienols na-egbochi nchịkọta platelet n'elu arịa ọbara ma na-echebe endothelium vaskụla, ya mere a na-ewere ya na ọ nwere mmetụta nke igbochi atherosclerosis na ọrịa obi.

Ọrụ ndu nke Tocotrienols nnukwu

Tocotrienols na tocopherols nwere usoro ndị yiri ya, yabụ tocotrienols nwekwara ụfọdụ ọrụ nke tocopherols, dị ka antioxidants [17]. Ebe ọ bụ na tocotrienols nwere unsaturated phytyl n'akụkụ ụdọ, tocotrienols nwere ụfọdụ ọrụ dị iche na tocopherols. Dịka ọmụmaatụ, ụdọ akụkụ nke tocotrienol na-enweghị nke na-enyere ha aka ịbanye nke ọma n'ime akwa nke nwere abụba juru eju. A na-ekesa anụ ahụ, dị ka imeju na anụ ahụ ụbụrụ, nke ọma na abụba abụba nke membranes cell, si otú a na-enwe ọrụ antioxidant dị elu na mmetụta scavenging free radical; Agbụ akụkụ nke tocotrienols nwere ike ịbawanye metabolism nke farnesol dị n'etiti ngwaahịa metabolic, si otú a na-egbochi ọrụ hydroxymethylglutaryl coenzyme A reductase (HMG-CoA reductase), yabụ tocotrienols nwere ọrụ nke iweda cholesterol; tocotrienols nwekwara ihe mgbochi angiogenic, na ikike ị nweta cellular dị okpukpu 70 karịa tocopherol.

Asambodo

YTBIO na-agba mbọ inye ndị ahịa ihe kacha mma Tocotrienols ntụ ntụ dị ọcha na ọrụ ka onye ọ bụla na-azụ ahịa nwee ike ịnụ ụtọ nri eke, ahụike yana oke mma. Ọ bụrụ na ị nwere ajụjụ ọ bụla ma ọ bụ mkpa gbasara ngwaahịa anyị, biko nweere onwe gị ịkpọtụrụ anyị, anyị ga-azaghachi gị ozugbo enwere ike.

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