CAPE ntụ ntụ

Nkọwa: 99%
Usoro nchọpụta: HPLC
CAS: 104594-70-9
Usoro ihe omimi: C17H16O4
Onu ogugu oke: 284.31
EINECS: 627-151-0
Mbupu ọsọ: 1-3 ụbọchị
Ngwaahịa: Ọ dị na ngwaahịa
Asambodo: HACCP, HALAL, KOSHER, ISO9001, ISO22000, FDA
MOQ: 25KG
Ngwugwu: 25kg / gbọmgbọm
Ndị na-ere ahịa: ọ bụghị maka ndị ahịa ọ bụla

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Kedu ihe bụ caffeic acid phenethyl ester?

Caffeic acid phenethyl ester nwere usoro, nke a na-akpọ CPAE, bụ otu n'ime ihe ndị bụ isi na-arụ ọrụ nke propolis ma dị irè megide nje virus herpes. Nje virus ndị ọzọ na-egbochi ihe ndị dị na propolis gụnyere adenovirus na nje influenza.

Ọdịdị nke Caffeic acid phenethyl ester nwere usoro phenyl 0-dihydroxy (catechol), nke bụ ihe a na-ahụkarị maka ịchacha radicals efu. Ọ nwekwara abụọ ortho-ọnọdụ phenolic hydroxyl otu, nke na-eme ka eletrọn njupụta na benzene mgbanaka elu na nnọọ mfe auto-oxidize na ịzụlite agba. Bors et al. kọrọ na usoro mgbanaka 0-dihydroxybenzene na-arụ ọrụ dị mkpa na mmetụta antioxidant nke flavonoids. Ngwakọta kemịkalụ nke propolis na mpaghara dị iche iche dị iche iche, yabụ ọdịnaya CAPE dịkwa iche. Nnyocha na-egosi na ọdịnaya CAPE dị na propolis na-emepụta na China dị elu, na-eru 15 ~ 25mg / g, ebe propolis emepụtara na Brazil enweghị CAPE. Ụlọ nyocha na-eji caffeic acid na β-bromoethylbenzene dị ka akụrụngwa na potassium phosphate dị ka ihe na-eme ka caffeic acid phenethyl ester na-emepụta ihe ruru 60%.

Ọdịdị chemical nke CAPE

Ọdịdị nke CAPE nwere ortho-dihydroxy (catechol) phenyl Ọdịdị, nke bụ ihe a na-ahụkarị nke na-eme ka radicals nweere onwe ya. Ọ nwekwara akụkụ abụọ nke phenolic hydroxyl ortho, nke na-eme ka njupụta elektrọn na mgbanaka benzene dị elu ma dị mfe auto-oxidizes. Mmepe agba. Bors et al. kọrọ na usoro mgbanaka o-dihydroxybenzene na-arụ ọrụ dị mkpa na mmetụta antioxidant nke flavonoids. Njikọ okpukpu abụọ na ọnọdụ 2' na 3' nke CAPE na-arụkwa ọrụ nke ọma, nke nwere ike ịkwalite ikike antioxidant ya. Ọdịdị nke phenethyl ester group nke CAPE dịkwa oke mkpa maka ọrụ ndụ ya. Ọ nwere ike ịkwalite ikike nke CAPE ịbanye n'ime akpụkpọ ahụ cell ma na-arụ ọrụ physiological na pharmacological.

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Mmetụta physiological na ọgwụ ọgwụ nke CAPE

CAPE ntụ ntụ nwere ọtụtụ ọrụ physiological na ọgwụ ọgwụ. Ọ nwere antioxidant, mgbochi mkpali, mgbochi nje na mgbochi mkpali Njirimara. CAPE bụ ihe mgbochi kpọmkwem nke ihe nuklia ma nwee ike ịgbanwe ọnọdụ redox ma mee ka apoptosis pụta. CAPE nwekwara ike inwe mmetụta mgbochi uto na ụdị mkpụrụ ndụ agbanwe agbanwe.

1. Mmetụta antioxidant

Ọdịdị CAPE nwere usoro catechol, nke bụ antioxidant siri ike. Ọnụ ọgụgụ dị ukwuu nke ọmụmụ egosila na CAPE na 10uM nwere ike igbochi mmepụta nke ihe ndị na-arụ ọrụ oxidative na neutrophils ma gbochie usoro xanthine oxidase. Nnyocha achọpụtala na ihe ndị bụ isi antioxidant na propolis bụ CAPE, caffeic acid, quercetin, kampiferol, galangal na caffeic acid cinnamyl. N'ime ha, propolis nwere CAPE nwere ọrụ antioxidant siri ike karịa propolis na-enweghị CAPE, na CAPE Ọrụ ahụ siri ike karịa ọrụ antioxidant nke galangal, na-egosi na CAPE bụ akụkụ dị mkpa nke mmetụta antioxidant. Ozyurt et al. mụọ ọrụ antioxidant nke propolis wepụ megide nnukwu mmerụ ahụ akụrụ na oke ma gosi na mmetụta antioxidant nke propolis wepụ dị mma karịa nke VE, na CAPE bụ otu n'ime ihe ndị bụ isi. Nnyocha na mmetụta nke CAPE na lipid peroxides na serum nke oke ọkụ na-achọpụta na CAPE nwere ike ibelata oriri nke SOD site n'iwepụ ihe ndị na-emeghachi omume oxidative na igbochi ọrụ xanthine oxidase (XO) na NOS, si otú ahụ na-arụ ọrụ antioxidant. .

2. Usoro mgbochi na mmetụta mgbochi mkpali

Nnyocha na-egosi na CAPE nwere mmetụta mgbochi mkpali dị ịrịba ama. CAPE nwere mmetụta mgbochi mkpali na nnukwu na-adịghị ala ala ahụkarị mbufụt, formaldehyde-induced na antigenic enhancer ọrịa ogbu na nkwonkwo, carrageenan na prostaglandin E2-induced edema mbufụt ma ọ bụ ikuku sac mbufụt, na owu transplant granuloma. Tụkwasị na nke ahụ, CAPE nwekwara mmetụta immunomodulatory, nke nwere ike ịgbanwe usoro cell nke akụkụ ahụ na-adịghị ahụkebe thymus na splin na ahụ na-egbuke egbuke, na-ebelata ibu nke thymus. CAPE nwere ike ibelata ọnụ ọgụgụ mkpụrụ ndụ T ozugbo ma ọ bụ na-apụtaghị ìhè.

3. Mmetụta na-achịkwa obi obi

CAPE ntụ ntụ nwere ike inwe usoro eji eme ihe na arịa ọbara. N'otu aka ahụ, ọ na-arụ ọrụ NO ntọhapụ na obere mkpokọta, na n'aka nke ọzọ, ọ na-egbochi mgbanwe nke calcium ion n'ime na n'èzí sel na elu mkpokọta. Nsonaazụ ndị a na-egosi uru nke CAPE na propolis nwere ike ime na mgbochi, nke nwere ike ịzere nsogbu nke ọma mgbe a gbasasịrị akwara thoracic na thoracoabdominal.

4. Ọrụ ndu ndị ọzọ

Na mgbakwunye na mgbochi mkpali ya, ihe mgbochi na usoro nchịkwa obi, Phenethyl kọfị A kọwo na ọ nwere ihe ndị ọzọ dị ndụ n'ime afọ ndị na-adịbeghị anya. CAPE nwere ike igbochi ọrụ nke HIV-1 ma gbochie nhazi oxygen anions (superoxide) nke na-emepụta site na auto-oxidation nke β-mercaptoethanol. CAPE na-egosipụtakwa mgbochi bara uru nke ọrụ xanthine oxidase na iguzogide peroxidation lipid.

ngwa

CAPE nwere ike ịkwalite mgbake nke ọrụ moto hind limb na oke SCI. Nsonaazụ nke HE staining na Nissl na-eme ka ọkpụkpụ azụ azụ na-egosi na CAPE nwere mmetụta nchebe na anụ ahụ na-ahụ maka ọkpụkpụ azụ na neurons, n'etiti nke ìgwè dị elu nwere mmetụta nchebe ka mma. Nsonaazụ nnwale ndị ọzọ bụ isi nke RT-qPCR gosipụtara na ụkpụrụ CAPE nke ụzọ akara anọ dị n'elu nwere ike jikọta na igbochi okwu EGFR, JUN, MMP9 na PTGS2 na ịkwalite ngosipụta nke mkpụrụ ndụ ESR1.

CAPE nwere ike ime ka e guzobe autophagy site na igbochi ụzọ akara AKT/mTOR, si otú ahụ na-egbochi mgbasa nke HSC-T6 cell.

Caffeic acid phenethyl ester na-ebelata nrụgide oxidative na semen ezi echekwara na ọnụ ụlọ okpomọkụ site na ụzọ akara AMPK/FOXO3a.

CAPE nwere ike igbochi peroxidation lipid, na-egbochi nchịkọta platelet iji gbochie ịmepụta thromboembolism, na-egbochi ụdị cytokines dị iche iche na-alụso ọrịa ọgụ iji kwalite ọgwụgwọ ọnya; N'otu oge ahụ, caffeic acid phenethyl ester bụkwa ihe dị ike nke kappa B (NF-κB) ọrụ Inhibitors. Otú ọ dị, n'ihi mgbanaka benzene na ester nhazi nke phenethyl caffeate, solubility dị oke ala, naanị 23 μg / m L na 25 ° C.

CAPE ntụ ntụ

Phenethyl caffeate soplaya

Yuantai Organic Bio na-agba mbọ inye ndị ahịa ihe kacha mma nnukwu CAPE ntụ ntụ na ọrụ ka onye ọ bụla na-azụ ahịa nwee ike ịnụ ụtọ nri eke, ahụike yana oke mma. Ọ bụrụ na ị nwere ajụjụ ọ bụla ma ọ bụ mkpa gbasara ngwaahịa anyị, biko nweere onwe gị ịkpọtụrụ anyị, anyị ga-azaghachi gị ozugbo enwere ike.

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