Caffeic acid ntụ ntụ

Nkọwa: 98%
Usoro nchọpụta: HPLC
CAS: 331-39-5
Usoro molecular: C9H8O4
Onu ogugu oke: 180.16
EINECS: 206-361-2
Ebe mgbaze 211-213 Celsius (dec.) (ọkụ.)
Ebe esi esi 272.96°C (atụmatụ siri ike)
Njupụta 1.2933 (atụmatụ siri ike)
Mbupu ọsọ: 1-3 ụbọchị
Ngwaahịa: Ọ dị na ngwaahịa
Asambodo: HACCP, HALAL, KOSHER, ISO9001, ISO22000, FDA
MOQ: 25KG
Ngwugwu: 25kg / gbọmgbọm
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Kedu ihe bụ caffeic acid?

Caffeic acid ntụ ntụ bụ organic acid nwere usoro kemịkalụ C9H8O4. Ọ bụ ntụ ntụ kristal na-acha odo odo, na-agbaze na mmiri ọkụ, ethanol, na obere soluble na mmiri oyi. Enwere ike iji ya n'enweghị nsogbu na ihe ịchọ mma ma nwee ọtụtụ ọrụ antibacterial na antiviral. .


A na-ahụkarị caffeic acid na ihe ndị sitere na ya na ụfọdụ nri na ọgwụ ọdịnala ndị China ma na-ekesa metabolites nke abụọ na osisi. A na-ejikọta caffeic acid na ihe ndị sitere na ya na osisi site na ụzọ shikimic acid, site na phenylalanine ruo cinnamic acid site na deamination, wee nweta ya na cinnamic acid. Otu o-diphenolic hydroxyl dị na mgbanaka benzene bụ saịtị na-arụ ọrụ nke caffeic acid na usoro ya. Ka ikike iwepụta elektrọn nke ihe nọchiri anya na mgbanaka benzene na-esiwanye ike, ọrụ ndụ ya na-esiwanye ike. Dị ka ogige eke dị mma ma dị irè, caffeic acid na ihe ndị na-emepụta ya nwere ihe omume dị ndụ dị ka antioxidant, free radical scavenging, mgbochi mkpali, antiviral, antibacterial, na mgbochi ọrịa. Na mgbakwunye, ha bara uru n'ịgwọ ọrịa obi na ọrịa cerebrovascular, meziwanye ọrịa shuga, mgbochi imeju fibrosis na akụkụ ndị ọzọ enwetawokwa nlebara anya zuru oke.

Enwere ụzọ abụọ bụ isi biosynthetic maka ihe nrụpụta caffeic acid macromolecular. Otu bụ ụzọ iji mepụta rosmarinic acid na salvianolic acid components site na iji 4-coumaric acid na 4-hydroxyphenyllactic acid dị ka ihe mmalite. Ọ kachasị dị na n'etiti osisi nke genus Salvia nke ezinụlọ Labiatae nke Salvia miltiorrhiza nọchiri anya ya, nke abụọ na-eji quinic acid, caffeic acid na ferulic acid dị ka ihe mmalite iji mepụta ihe mejupụtara chlorogenic acid, nke a na-ahụkarị na osisi nke ezinụlọ Lonicera. Honeysuckle nọchiri anya Lonicerae. n'etiti osisi nke genus. Chlorogenic acid bụ ester emepụtara site na mmeghachi omume caffeic acid na quinic acid. Ngwakọta ya nwere ọtụtụ akụkụ anaghị akwụsi ike dị ka ester bonds, unsaturated double bond na polyphenols. Ya mere, a na-ahụkarị acid chlorogenic n'ụdị dị iche iche na osisi. Isomers na-ebikọ ọnụ.

Olee uru?

Ọrụ mgbochi

N'ime afọ ndị na-adịbeghị anya, nchọpụta achọpụtala na caffeic acid na ihe ndị na-emepụta ya nwere ezigbo nje na-egbochi influenza na mgbochi nje HIV. Caffeic acid nwere ike igbochi mgbasa nke nje influenza A ma gbochie mgbasa nke nje ịba ọcha n'anya C na mmalite nke ọrịa ịba ọcha n'anya C. Caffeic acid phenethyl ester, nke sitere na caffeic acid, bụ ihe sitere n'okike achọpụtara n'afọ ndị na-adịbeghị anya nwere ihe mgbochi nje HIV doro anya. Na mgbakwunye, lithospermic acid na salvianolic acid B nwere ọrụ siri ike na igbochi ụdị nje virus immunodeficiency mmadụ I (HIV-I) integrase, yana IC5 nke 0.83 na 0.48 mol/L n'otu n'otu, na-atụ anya na ọ ga-aghọ ọgwụ ọhụrụ eke maka ọgwụgwọ ọrịa AIDS. . Na mgbakwunye na nje nje HIV, a na-ejikọta caffeic acid na quinic acid site na mmeghachi omume esterification iji mepụta usoro nke ogige phenolic acid, nke a na-akpọ caffeoylquinic acid, nke ihe mejupụtara chlorogenic acid nọchiri anya ya. Ụdị onyinye a dị n'ọtụtụ ebe n'ime osisi ndị dị ka Asteraceae, Fabaceae, Apiaceae, Convolvulaceae, wdg, nchọpụta achọpụtala na ụdị ihe a nwere ezigbo ọrụ mgbochi ma nwee ike igbochi nje influenza na nje ịba ọcha n'anya B. Nnyocha e mere n'oge na-adịbeghị anya achọpụtala na chlorogenic acid na caffeic acid dị na forsythin nwere ike igbochi mgbasa nke nje gastroenteritis porcine transmissible (TGEV) na mkpụrụ ndụ testicular porcine (ST). N'ime ha, caffeic acid nwere ike ibelata ọrụ nje. A na-atụ anya na a ga-emepụta ya ka ọ bụrụ ọgwụ mgbochi nje.

Antibacterial, mgbochi ọrịa

Caffeic acid na ihe ndị sitere na ya bụ ihe fungicides eke nwere ike igbochi ụdị fungal na nje nje. Nnyocha egosiwo na usoro nje bacteria nke ihe mejupụtara caffeic acid na-ejikọta ya na njirimara antioxidant siri ike ya. Salvianolic acid A na Salvia miltiorrhizae nwere ezigbo mgbochi mkpali ọrụ mgbe ultrasonic mmịpụta. Acid chlorogenic dị na Panax notoginseng, honeysuckle na Eucommia ulmoides nwere ọrụ antibacterial siri ike ma nwee ike ịmepụta ya dị ka ihe nchekwa nri eke. Nnyocha ndị ọzọ egosila na mmetụta mgbochi nke chlorogenic acid components na E. coli bụ n'ihi eziokwu ahụ bụ na ihe ndị a nwere ike ibibi mgbidi cell cell na akpụkpọ ahụ, na-eduga n'ịba ụba nke cell permeability, nke na-akpata nkwụsị nke cell. ọdịnaya na-eduga na cell apoptosis. .

Ọrịa cardiovascular

A na-eji nkwadebe Salvia miltiorrhiza eme ihe na ọgwụgwọ ụlọ ọgwụ nke ọrịa obi na akwara ozi. Ihe ndị bụ isi kemịkalụ na-egosipụta mmetụta ọgwụ ọgwụ bụ salvianolic acid na ihe ndị ọzọ na-emepụta caffeic acid. Nnyocha achọpụtala na ihe ndị dị na salvianolic acid nwere mmetụta mgbochi siri ike megide mmerụ ahụ ischemia-reperfusion nke ụbụrụ, nwere ike igbochi nchịkọta platelet, ma nwee mmetụta mgbochi thrombotic dị mma. Mkpokọta salvianolic acid nwere ike igbochi thrombosis ma belata ọkwa endothelin plasma na thromboxane B2 mgbe ischemia cerebral gasịrị.

Fibrosis mgbochi imeju na mmetụta hepatoprotective

Fibrosis imeju na-ezo aka n'ụzọ na-adịghị mma nke anụ ahụ jikọtara na imeju nke ihe dị iche iche na-akpata ọrịa kpatara. Ọ bụ n'ihi mmebi nke imeju parenchyma anụ ahụ na biliary usoro. Nnyocha achọpụtala na ma salvianolic acid A na B na-egosipụta ọrụ hepatoprotective siri ike, na lithospermic acid nwere ike iguzogide mmebi imeju nke nrụgide oxidative kpatara. Danshensu nwere ike igbochi fibrosis imeju site na ụzọ akara MEK/ERK, yana caffeic acid phenethyl ester nwere ike iguzogide nrụgide oxidative ma gbochie ọrụ nke mkpụrụ ndụ hematopoietic stem cell (HSC), ya mere o nwere njirimara mgbochi imeju fibrosis.

ọgwụgwọ mmetụta na-arịa ọrịa shuga

N'afọ ndị na-adịbeghị anya, ọmụmụ egosila na enwere njikọ dị n'etiti ọrịa shuga na nrụgide oxidative, na mmetụta antioxidant nke caffeic acid na ihe ndị sitere na ya na-ekerekwa òkè dị mma na ọgwụgwọ ọrịa shuga. Caffeic acid nwere ike ibelata nnabata nke glucose site na mkpụrụ ndụ endothelial, na-akwalite mwepu nke glycogen n'ime imeju, ma na-achịkwa mmetụta nke pancreatin site na ịbawanye nnabata glucose nke adipocytes, si otú a na-ebelata ọkwa shuga dị n'ọbara. Ihe ndị na-emepụta caffeic acid caffeic acid methyl ester (CAME), caffeic acid ethyl ester (CAEE), na caffeic acid phenethyl ester (CAPE) nwere ike ibelata nnabata glucose site na mkpụrụ ndụ C2C12. Sinapic acid nwere ike ibelata ọkwa glucose dị elu na-ebute oke vaskụla vaskụla mkpụrụ ndụ dị nro ma kwalite apoptosis cell site na igbochi ọrụ PKC/P38, enwere ike iji ya mee ihe maka mgbochi na ọgwụgwọ nke nsogbu ọrịa shuga. Salvianolic acid A nwere ike ịgwọ ọrịa shuga site na ịgbalite AMPK iji mezie mitochondria.

Ntuziaka ngwa

Site na ọganihu nke nyocha sayensị, usoro ụzọ biosynthetic nke caffeic acid na ihe ndị sitere na ya na-aghọwanye nke zuru oke. Mmekọrịta nhazi-mmekọrịta nke caffeic acid na usoro ya ka aghọtakwara na mbụ. Dịka ọmụmaatụ, ọrụ ndụ ya nwere njikọ chiri anya na otu hydroxyl na mgbanaka benzene ya. Mgbe hydrogen dị na mgbanaka benzene jiri ụfọdụ ndị na-adọta eletrọn dochie ya, ọrụ ndụ ya na-esiwanye ike. Enwere ike nweta nke a site na kemịkalụ Usoro sịntetịt na-agbanwe ihe ndị nọchiri anya na mgbanaka benzene ka ọ bụrụ ebumnuche na imepụta ihe ọhụrụ caffeic acid iji kwalite ọrụ ndu ha.

     

Caffeic acid ntụ ntụ na usoro ya nwere ihe omume ndu dị ka antiviral, antibacterial, mgbochi ọrịa, na ọgwụgwọ nke ọrịa obi na cerebrovascular. Ejirila ha na ngalaba ahụike. Ụfọdụ ọgwụ maka ọgwụgwọ ọrịa obi na ọrịa cerebrovascular nwere caffeic acid na ihe ndị sitere na ya. , dị ka mbadamba caffeic acid nwere ike iji gwọọ leukopenia, na sodium ferulate nwere ike iji gwọọ atherosclerosis. Na mgbakwunye na ngwa ha na ngalaba ahụike, caffeic acid na ihe ndị sitere na ya aghọwokwa ebe nyocha ọhụrụ na mpaghara ndị ọzọ.

Dịka ọmụmaatụ, caffeic acid na ihe ndị sitere na ya nwere ọrụ antioxidant na sistem emulsification nri ma nwee ike ịgbatị ndụ nri. Caffeic acid na ester ester na-arụ ọrụ antioxidant na usoro emulsification nke Mayonezi, mmiri ara ehi na mmanụ azụ kpụrụ. Ọrụ antioxidant nke caffeic acid na ihe ndị sitere na ya na-eme ka ọ bụrụ ihe mgbakwunye na nchekwa na nchekwa nri. Dị ka ngwaahịa eke dị mma ma dị irè, caffeic acid na ihe ndị sitere na ya nwere ọrụ dị iche iche nke ndu. A kwenyere na site na nyocha miri emi, a ga-ejikwa ha dị ka ihe mgbakwunye nri na nri nri n'ọdịnihu.

Caffeic acid ntụ ntụ

Caffeic acid soplaya

Yuantai Organic Bio na-agba mbọ inye ndị ahịa ihe kacha mma Otutu caffeic acid ntụ ntụ na ọrụ ka onye ọ bụla na-azụ ahịa nwee ike ịnụ ụtọ nri eke, ahụike yana oke mma. Ọ bụrụ na ị nwere ajụjụ ọ bụla ma ọ bụ mkpa gbasara ngwaahịa anyị, biko nweere onwe gị ịkpọtụrụ anyị, anyị ga-azaghachi gị ozugbo enwere ike.

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