Nnukwu vitamin E mmanụ

Gịnị bụ vitamin E?

Ọ bụ vitamin na-agbaze abụba, na ngwaahịa hydrolysis ya bụ tocopherol, nke bụ otu n'ime antioxidants kachasị mkpa. Ọ na-abụkarị soluble na organic solvents dị ka abụba na ethanol, insoluble na mmiri, kwụsiri ike okpomọkụ na acid, ejighị n'aka na alkali, mmetụta oxygen, na enweghị mmetụta na okpomọkụ, ma ọrụ nke vitamin E na-budata belata mgbe e ghere eghe. Tocopherol nwere ike ịkwalite secretion nke homonụ mmekọahụ, mụbaa ume na ọnụọgụ nke spam nwoke; na-amụba mkpokọta estrogen nke nwanyị, meziwanye ọmụmụ, gbochie ime ime, a pụkwara iji mee ihe iji gbochie ma na-agwọ amụghị nwoke, ọkụ ọkụ, oyi oyi, ọbara ọgbụgba capillary, ọrịa menopausal, na ịma mma. N'oge na-adịbeghị anya, a chọpụtakwara na ọ nwere ike igbochi mmeghachi omume lipid peroxidation na oghere anya, gbasaa arịa ọbara dị n'akụkụ, meziwanye mgbasa ọbara, ma gbochie ihe omume na mmepe nke myopia. Otu phenolic hydroxyl na mgbanaka benzene bụ acetylated, na ester na-hydrolyzed na phenolic hydroxyl otu iji mepụta tocopherol. Vitamin E, nke a makwaara dị ka tocopherol, na-agụnyekarị ụdị abụọ nke tocopherol na tocotrienol, ngụkọta nke 8 ogige, ya bụ α, β, γ, δ tocopherol na α, β, γ, δ tocotrienol. Ọ bụ mmiri mmiri viscous mmanụ na-acha ọla edo ma ọ bụ na-acha odo odo, nke na-enweghị isi, nwere isi dị nro pụrụ iche, nke a na-esighị ike n'ime mmiri, na-agbaze ngwa ngwa na ihe mgbaze organic dị ka acetone na abụba. Ọ kwụsiri ike na ìhè a na-ahụ anya, na-emebi n'okpuru ìhè ultraviolet, ọ kwụsiri ike na acid na okpomọkụ, ọ naghịkwa akwụsi ike na gburugburu alkaline. Ọ bụ ihe antioxidant dị mkpa nke nwere ike wepụ superoxide free radicals, na-egbochi peroxidation lipid, ma belata mmebi DNA oxidative, ya mere ọ nwere mmetụta mgbochi ịka nká.

Chemical Njirimara:

1. Solubility
Ọ bụ mmiri mmiri viscous na-acha odo odo ma ọ bụ na-acha odo odo, nke na-adị mfe mgbaze na ethanol acetone anhydrous, ether petroleum ether, na mmiri na-adịghị ike.
2. Hydrolysis
Enwere acetylated phenolic hydroxyl otu na mgbanaka benzene, nke nwere ike hydrolyzed iji mepụta tocopherol n'efu mgbe ọ na-ekpo ọkụ na acidic ma ọ bụ alkaline ngwọta, ya mere a na-ejikarị ya dị ka adịghị ọcha pụrụ iche.
3. Oxidation:
Ọ na-ekpo ọkụ na-ekpo ọkụ n'okpuru ọnọdụ anaerobic na agaghị ebibi ọbụna mgbe a na-ekpo ọkụ na 200 Celsius, ma ọ na-enwe mmetụta nke ọma na ikuku oxygen na ìhè na ikuku nwere ike ime ya. Ngwaahịa oxidation ya bụ a-tocoquinone na a-tocopherol dimer.
4. Njirimara absorption ultraviolet
Enwere otu phenolic hydroxyl na mgbanaka benzene na nhazi nke ngwaahịa a, nke nwere nnabata ultraviolet. Ihe ngwọta ethanol nke anhydrous ya nwere oke mmịpụta na ogologo ogologo nke 284nm, yana ọnụọgụ absorption bụ 41.0 ~ 45.0.

Mmetụta:

1. Mwepụ ntụpọ, ịma mma, nlekọta anụ ahụ na mgbochi ịka nká
Ọ nwere mmetụta antioxidant ma nwee ike neutralize na ọgụ free radicals. Free radicals bụ isi ihe na-ebute ntụpọ, wrinkles na ịka nká n'ihu anyị. Ọdịnaya dị elu nke VE nwere ike ime ka collagen akpụkpọ ahụ dịkwuo ike, melite mgbasa ọbara, ma wepụ ihe ndị na-akpata free radicals nke ikpughe anyanwụ, mmetọ na nchekasị kpatara, iji lụso ịka nká ọgụ n'ime na n'èzí.

2. Chebe arịa ọbara, gbochie thrombosis, na igbari mkpụkọ ọbara
Ọ nwere ike igbochi mkpụkọ ọbara nke mgbawa nke arịa ọbara kpatara. Mgbe mkpụrụ ndụ ndị dị na arịa ọbara gbawara, ha ga-ada. Mkpụrụ ndụ ndị nwụrụ anwụ dara ada ga-ekekọta ụfọdụ cholesterol, abụba, na calcium n'efu, wee ghọọ ihe dị ka thrombus. Nke a thrombus na-asọpụta n'ime ahụ na ọbara gị. Ọ bụrụ na ọ na-ezute nkwụsịtụ, ọ bụrụ na nkwụsịtụ a dị ntakịrị, enwere ike igbochi thrombus n'ebe ahụ, ọ dịkwa mfe ịnweta ụbụrụ ụbụrụ, myocardial infarction, na ọrịa strok. Maka thrombus nke etolitelarị, VE nwere ike igbari ya. VE bụ ọgwụ mgbochi obi dị oke nchebe, mana ọ nweghị mmetụta ọ bụla na-egbu egbu nke anticoagulants.

3. Gbochie anaemia na jaundice kpatara mgbawa nke mkpụrụ ndụ ọbara uhie
Mkpụrụ ndụ ọbara uhie nkịtị nwere ndụ nke ụbọchị 120. Mgbe nsị dị n'ime ahụ na-abawanye, ọ ga-adị mkpụmkpụ nke ukwuu. Mgbe mkpụrụ ndụ ọbara uhie gbawara ngwa ngwa, ọ bụrụ na enzymes nke anụ ahụ emebighị ha na vitamin B ewereghị ya nke ọma, ọtụtụ mkpụrụ ndụ ọbara uhie ga-anwụ, na-ebute anaemia na jaundice. Ọzọkwa, mgbe nwa ebu n'afọ na-etolite n'ime ahụ nne, ọrụ imeju ezughị oke. Mgbe nne dị ime, na-eri nri n'èzí na enweghị vitamin E, nwa ebu n'afọ ga-abụ hypoxic ma nwee jaundice mgbe a mụsịrị ya.

4. Belata nhazi anụ ahụ
Imeju bụ nnukwu microvessel. A na-enye cell imeju ọ bụla nri nri na oxygen site na microvessels. Ọ bụrụ na enweghi E, microcirculation ga-ada ogbenye, abụba, protein, na cholesterol ga-agbakọta iji mee ka imeju na-ebu abụba na cholesterol dị elu.
A ga-emerụ mkpụrụ ndụ imeju n'ihi ụkọ nri zuru oke. Imeju ga-amalite ọrụ nrụzi onwe ya. N'ihi ụkọ nri ezughị ezu, a ga-emeziwanye ya, si otú ahụ na-etolite fibrosis, anụ ahụ ga-apụta, na ike ga-apụta. Cirrhosis nke imeju nwere imeju na-ebu abụba ruo ogologo oge n'ihi mgbasa nke imeju adịghị mma. Ya mere, ndị nwere imeju nwere abụba kwesịrị ịgbakwunye vitamin. Ọ nwere ike ichekwa lecithin, gbarie ma were abụba na protein bekee, ma gbochie ha ịbụ oxidized. Lecithin nwere ike ime ka nri ndị a kwakọbara nke ọma ma melite microcirculation imeju. Ya mere, ọrịa imeju nwere ike igbochi ma gwọọ ya.

5. meziwanye mgbasa ọbara,
chebe arịa ọbara, na-echebekwa cell membranes. Ọ bụghị naanị arịa ọbara, kamakwa mpaghara dị n'akụkụ anya na-eji nnukwu capillaries kpuchie ya. Mgbe vitamin E na-enweghị, ngbanwe nke arịa ọbara adịghị mma. Mgbe ị na-ele ihe dị nso, arịa ọbara na-agbakọ, ma ha enweghị ike ịpụta, nke na-aghọ myopia. Mgbe ị na-ele ihe ndị dị anya anya, capillaries na-agbasawanye na ha enweghị ike ịlaghachi azụ, nke na-aghọ strabismus na anya gafee.

6. Anti-oxidation na mgbochi mkpali
Mwepụ na-adịghị mma n'efu n'ime ahụ, mmụba oxidative, na ọnya na-adịghị ala ala bụ isi ihe kpatara ịka nká na ọrịa dị iche iche na ahụ mmadụ. VE nwere ike wepu radicals n'efu, belata nrụgide oxidative n'ime ahụ, yana ịkwado nri ndị ọzọ iji wepụ mbufụt na ahụ. Ọ nwere ike igbochi kọlesterol nke ọma ka ọ ghara ịdị na-ekpo ọkụ, na-echekwa ahụike nke akpụkpọ ahụ cell, ma chebe VA ka ọ ghara ịdị na-ekpo ọkụ. Ya mere, ọ na-enwe mmetụta dị mma na ọrịa obi, na-egbu oge ịka nká, na nsogbu dị iche iche na-adịghị ala ala na ọrịa na-adịghị ala ala.

7. igbochi ọrịa Alzheimer
Ọrịa Alzheimer metụtara VE n'ime ọbara. Ndị agadi nwere ọdịnaya VE dị elu nwere ohere dị ala nke ịta ahụhụ site na ọrịa Alzheimer.
Enwere nnwale metụtara ndị agadi 232 karịrị afọ 80. Ná mmalite, ọ dịghị nke ọ bụla n'ime ha nwere ọrịa Alzheimer, ma n'ime afọ 6 sochirinụ, a chọpụtara na 57 n'ime ha nwere ọrịa Alzheimer. Ndị nchọpụta ahụ kewara ma jiri ndị nwere VE kachasị elu na nke kachasị ala n'ọbara ha. Nsonaazụ gosiri na ndị agadi nwere oke VE n'ọbara ha nwere ohere dị ntakịrị nke ịmalite ọrịa Alzheimer. Mgbe e wepụrụ ihe ndị ọzọ, ndị nchọpụta chọpụtara na ihe ize ndụ nke ndị agadi nwere ọrịa Alzheimer nwere ike ibelata site na 45-54% ma ọ bụrụ na enwere VE dị elu n'ọbara ha.

Nwa

Nhazi Capusle

Nhazi mbadamba

Usoro ihe ọṅụṅụ siri ike

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