Nnukwu Melatonin ntụ ntụ

Aha ngwaahịa: Melatonin / Melatonin wepụ / Melatonin ntụ ntụ
Usoro Molekụl: C13H16N2O2
Molekụla arọ: 232.28
Ọdịdị: White crystalline fine powder
Nọmba .: 73-31-4
Nkọwapụta: Melatonin 99% HPLC
Ngwugwu: 10 ~ 25Kg / Drum 1kg / Aluminom foil bag
Ebuka: Dị
Ọnọdụ nchekwa: Ngwaahịa a kwesịrị ka edochi ya ma kpuchie ya, chekwaa ya na nkụ
Asambodo:ISO9001,ISO22000,Kosher,Halal,HACCP
Mbupu ọsọ: 1-3 ụbọchị

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Gịnị bụ melatonin ntụ ntụ?

Melatonin bụ hormone endogenous nke akụkụ ụbụrụ mmadụ na-emepụta nke a na-akpọ pineal gland. A makwaara ya dị ka hormone abalị. Ọ bụ ozi dị mkpa nke na-enyere ahụ aka ịbanye ọnọdụ abalị. Nnyocha e mere ugbu a achọpụtala na nzuzo nke melatonin nwere ụda okirikiri. Ọ na-adị ala n'ehihie, jiri nwayọọ nwayọọ na-abawanye mgbe chi jiri, na-erute n'elekere 23:00 ruo 3:00 nke ụtụtụ, wee daa nke ọma tupu chi ọbụbọ.


Nnukwu Melatonin ntụ ntụ bụ hormone a na-emepụta na pineal gland nakwa na osisi na microorganisms. Achọpụtara ma kpọọ aha ya site n'aka ọkà mmụta gbasara akpụkpọ anụ America bụ Aaron Lerner na 1958. Ọ na-emetụtakarị ya na usoro ịgba ọsọ na usoro ọmụmụ oge.


N'ọtụtụ anụmanụ, a na-emepụta melatonin ma na-ezobe ya n'abalị (nke a gbanwere site na tryptophan). A na-arụkwa ya n'ọtụtụ anụ ahụ na sel, gụnyere retina, mkpụrụ ndụ ụmị ọkpụkpụ, platelet, eriri afọ, akpụkpọ ahụ, ma ọ bụ lymphocytes. cell.


Melatonin ntụ ntụ dị ọcha ndị na-anabata ihe na-agbasasị n'ime ahụ dum ma yie ka ọ bụ akara ngosi physiological multi-purpose nke na-etinye aka na njikwa nke ọtụtụ usoro ihe ọmụmụ physiological, si otú ahụ na-emetụta ụra, mmeputakwa, molting, nzaghachi mgbochi ọrịa, ike itule na omume.


Tụkwasị na nke ahụ, ọ nwere ihe ndị na-akpata antioxidant kpọmkwem na nke na-apụtaghị ìhè, na e nwere ihe àmà siri ike na ogige a nwere ike igbochi mmetụta ọjọọ nke ụdị oxygen na-emeghachi omume na nitrogen na usoro dị iche iche.

Kedu ihe Pure melatonin ntụ ntụ na-eme?

1. Ọ dị mma maka ahụike ọkpụkpụ

Nnyocha e mere n'usoro gosiri na melatonin ọnụ na-abawanye osteocalcin. Usoro dị n'okpuru nwere ike jikọta ya na melatonin na-emetụta nhazi nke osteoblasts na osteoclasts site na ụmụ irighiri ihe dị ka MT2 melatonin receptor, MEK1/2 na MEK5, si otú a na-egbochi ọkpụkpụ ọkpụkpụ. Maka ụmụ nwanyị perimenopause na postmenopausal, melatonin nwere ike inwe mmetụta dị mma na ahụike ọkpụkpụ.


2. Ọ dị mma maka ịda mbà n'obi

Nnyocha e mere n'usoro gosiri na melatonin ọnụ nwere ike imeziwanye ịda mbà n'obi. Ọ bụrụ na ị nwere ịda mbà n'obi na mgbaàmà gị na-akawanye njọ mgbe ị naghị ehi ụra nke ọma, melatonin nwere ike inye aka.


3. Melite ọnụego ihe ịga nke ọma nke in vitro insemination artificial

Nlekọta ọnụ nke melatonin n'oge ọgwụgwọ fatịlaịza in vitro na-abawanye ọnụ ọgụgụ nke oocytes tozuru okè ma nwee ọchịchọ, n'agbanyeghị na ọ bụghị nke dị ịrịba ama, na-abawanye ọnụego afọ ime ụlọ ọgwụ. Maka ọgwụgwọ in vitro artificial insemination, melatonin nwere ike inye aka, mana ọ na-ejedebe site na obere ihe nlele na-achọkwu nyocha iji nyochaa ya ọzọ.


4. Bara uru maka njikwa ibu

Nnyocha egosiwo na mgbakwunye na nnukwu doses nke melatonin (usoro ọgwụgwọ sitere na 3 ruo 10 mg kwa ụbọchị, na oge ntinye aka sitere na 3 ruo 48 izu) nwere ike ibelata ibu ahụ.


5. bara uru maka ụmụaka nwere autism

Dị ka ọnụ ọgụgụ si kwuo, ihe ruru 89% nke ụmụaka nwere nsogbu ụra na-enwe nsogbu ụra, na ọnụnọ nke nsogbu ụra nwere ike inwe mmetụta na-adịghị mma na prognosis. A meta-analysis (gụnyere 5 randomized, abụọ-kpuru, placebo-achịkwa ọmụmụ banyere autism na ụmụaka) chọpụtara na ojiji nke melatonin nwere ike inye aka melite ihi ụra parameters (gụnyere ụra oge na oge na-ehi ụra). Na mgbakwunye, melatonin na-egosi na ọ na-eme ka omume ehihie dịkwuo mma na ndị nwere autism, na-enwe mmetụta ole na ole.


6. mmetụta mgbochi mkpali

Ọmụmụ ihe ahụ chọpụtara na mgbakwunye melatonin na-ebelata TNF-α (tumor necrosis factor) na IL-6 (interleukin-6), mana enweghi mmetụta dị na CRP (protein reactive protein C). Mgbakwunye Melatonin nwere ike inye aka belata ndị mgbasa ozi pro-inflammatory.


7. Ọ bara uru maka migraines

Nnyocha zuru oke (gụnyere 25 na-achịkwa ule a na-achịkwa na ngụkọta nke ndị ọrịa 4499 migraine) gosiri na melatonin ọnụ nwere ike inye aka melite ugboro ugboro nke migraine. N'ime ihe niile a nyochara, melatonin ọnụ 3 mg tupu ịlakpu ụra bụ ọgwụgwọ kachasị mma ma nwee ọganihu kachasị mma.


8. Mmalite isi ehighi ura

Isi ehighị ụra nke ọma bụ naanị ehighi ụra nke a na-akọwaghị. Ya bụ, ehighi ura nke na-esiteghị n'ọrịa, echiche uche ma ọ bụ ihe na-akpata gburugburu ebe obibi.


Ihe mgbaàmà bụ isi nke ehighị ụra nke ọma bụ isi ike ịmalite ma ọ bụ ịnọgide na-ehi ụra, ma ọ bụ inwe ụra na-adịghị mma nke na-adịru opekata mpe otu ọnwa. Melatonin na-enyere aka belata oge nchere tupu ịrahụ ụra ma na-abawanye oge ihi ụra zuru oke, na-eme ka ihi ụra dịkwuo mma.


9. Meziwanye ehighị ụra nke abụọ

Na mgbakwunye na ihe ndị bụ isi, ehighị ụra nke ọma nwekwara ihe nke abụọ, nke na-ebutekarị ọrịa, akwara ozi, gburugburu ebe obibi, ọgwụ ma ọ bụ isi mgbaka. Ihe ndị nke abụọ na-adịkarịkwa.


Ihe na-akpata ọrịa gụnyere mgbu, ọrịa thyroid, reflux acid, ọrịa akwara obi, ọrịa akpa ume (ọrịa na-adịghị ala ala obstructive pulmonary, asthma, apnea sleep, Central alveolar hypoxia syndrome), ụkọ akụrụ na-adịghị ala ala, nsogbu iri nri, arụ ọrụ thyroid , fibromyalgia, metụtara ịhụ nsọ. nsogbu ihi ụra, na afọ ime. Ihe na-akpata akwara ozi gụnyere isi ọwụwa, ọrịa Parkinson, na ndị ọzọ. Ihe ndị metụtara gburugburu ebe obibi gụnyere oke mkpọtụ, ísì ọjọọ, ọkụ na-egbuke egbuke ma ọ bụ oke okpomọkụ, ebe ọgwụ na ihe mgbaka gụnyere ịṅụbiga mmanya ókè, nsogbu nchekasị, nsogbu ọnọdụ uche, nsogbu ụjọ na ọrịa uche ndị ọzọ. Exogenous melatonin na-ebelata oge achọrọ iji hie ụra ma na-abawanye oge ụra zuru oke, mana ọ nweghị mmetụta dị ukwuu na ịrụ ọrụ nke ọma.


10. Meziwanye imeju abụba abụba

Mgbakwunye melatonin nke dị elu (ụgwọ kwa ụbọchị sitere na 6 ruo 18 mg, oge ikpe sitere na 4 ruo 56 izu) na-enyere aka belata aspartate alaninase (AST), alkaline phosphatase (ALP), na gamma -Glutamyltransferase (GGT).


11 Na-enyere aka n'ịgbanwe lag jet

Jet lag, nke a makwaara dị ka rhythm rhythm circadian, bụ nsogbu ihi ụra nke na-eme njem ngwa ngwa site n'ọtụtụ mpaghara oge, na-akpata ndakọrịta n'etiti ụda circadian nke anụ ahụ na gburugburu mpụta. melatonin nke ọnụ (na doses n'etiti 500mcg na 5mg) nwere ike inye aka gbochie ma ọ bụ belata jet lag ma yie ka ọ dị mma mgbe a na-ewere ya mgbe ụfọdụ maka obere oge.


12 Melite ọrịa Alzheimer

Ọrịa Alzheimer bụ ihe na-ebutekarị mgbaka na ndị agadi. Ihe ndị a na-ahụkarị bụ mbelata na ebe nchekwa, asụsụ, na ọgụgụ isi na-aga n'ihu. Tụkwasị na nke ahụ, nsogbu ụra na ọrịa circadian rhythm na-emekarị na ọrịa Alzheimer (karịsịa na mmalite nke ọrịa ahụ), a kọwakwara na ihe ruru 45% nke ndị ọrịa nwere ike inwe nsogbu ụra. Nnyocha egosiwo na ọgwụgwọ melatonin nwere ike ịbawanye oge ụra zuru oke n'abalị, mana ọ nweghị mmetụta dị ukwuu n'ịkwalite arụmọrụ ọgụgụ isi.

Otu dị mma maka nnukwu melatonin ntụ ntụ

01 okenye

Melatonin bụ ihe na-ehi ụra nke anụ ahụ mmadụ na-emepụta. Mbelata nke melatonin bụ isi ọwụwa nke ehighi ura.


Ịgbakwunye melatonin nwere ike iweghachi ọkwa melatonin na ọnọdụ ntorobịa, ebe ọ na-arụkwa usoro okike nke irighiri ụra nke ahụ mmadụ. Ọ nwere ike belata oge iji teta tupu ị lakpuo ụra na oge ịrahụ ụra, mezie ụda, melite ogo ụra, ma belata ọnụ ọgụgụ nke edemede n'oge ụra. Oge ihi ụra nke ìhè dị mkpụmkpụ na oke ụra miri emi na-adịte aka.


02 Ndị na-adịghị mma ụra

Melatonin nwere ike belata oge iji teta tupu ị lakpuo ụra na oge ịrahụ ụra, na-ebelata ọnụ ọgụgụ nke edemede n'oge ụra, na-ebelata ohere ihi ụra, na ịgbatị oge ụra miri emi, si otú ahụ na-eme ka ihi ụra dịkwuo mma.


03 Ndị mmadụ na-arịa ọrịa jet lag na ọrụ mgbanwe

Ihe nzuzo nke melatonin n'ime ahụ mmadụ nwere ụda circadian, yana ọtụtụ melatonin na-ezobe n'abalị.


Melatonin nwere ike ịtọgharịa elekere usoro ndụ nke anụ ahụ, mezie lag jet, dozie lag jet, nyere aka tụgharịa jet lag, ma melite ụra nke ndị ọrụ mgbanwe.

Kedu ka melatonin si arụ ọrụ

Ụra bụ nkwa dị mkpa maka ahụike mmadụ. Ụmụ mmadụ na-ehi ụra nanị otu ugboro n'ụbọchị kwa oge n'ihi ụda circadian a na-achịkwa nke ọma, nke neurons, neurotransmitters, hormones, na mkpụrụ ndụ ihe nketa na-achịkwa agụụ ụra, gụnyere adenosine, serotonin, na melatonin, n'etiti ndị ọzọ.

Melatonin, nke a makwaara dị ka hormone ụra, bụ akụkụ bụ isi nke usoro ụra ụra nke ahụ. Mmepụta ya na-abawanye n'ọchịchịrị, na-akwalite ụra nke ọma, ma na-enyere aka ịhazigharị okirikiri okirikiri nke ahụ. Ọ na-arụ ọrụ na MT1, MT2, na MT3 ndị natara n'ime ahụ. N'ime ha, ndị na-anabata MT1 na MT2 na-ahụ maka ịhazi ụda circadian na ụra, ya bụ, na-enyere aka ịkwalite ụra.

Nyochaa akụkọ banyere melatonin ntụ ntụ

ITEM

STANDARD

TNsonaazụ EST

Melatonin

≥99.0%

99.50% nke HPLC

Anụ ahụ & Kemịkalụ

ọdịdị

Nwepu-ọcha ntụ ntụ

Kwuru

Akụkụ Nkebi

Ngwunye 80-100

Kwuru

Ọnwụ na nkụ

≤0.5%

0.18%

Ash

≤0.1%

0.05%

Melting Point

117-120 ℃

118.5-119.0 ℃

Solubility

100% soluble

Kwuru

arọ metal

Total arọ ọla

≤10.0ppm

Kwuru

As

≤1.0ppm

0.27ppm

Nnwale Microbiological

Ọnụ Ọgụgụ Ogugu

≤1,000cfu / g

<15cfu/g

Akpụkpọ anụ na yist

≤100cfu / g

<10cfu/g

E.Coli

-adịghị mma

-adịghị mma

Salmonella

-adịghị mma

-adịghị mma

Ọrịa Staphylococcus Aureus

-adịghị mma

-adịghị mma

Asambodo

YTBIO na-agba mbọ inye ndị ahịa ihe kacha mma Pure nnukwu melatonin ntụ ntụ nnukwu ntụ ntụ na ọrụ ka onye ọ bụla na-azụ ahịa nwee ike ịnụ ụtọ nri eke, ahụike yana oke mma. Ọ bụrụ na ị nwere ajụjụ ọ bụla ma ọ bụ mkpa gbasara ngwaahịa anyị, biko nweere onwe gị ịkpọtụrụ anyị, anyị ga-azaghachi gị ozugbo enwere ike.

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Ngwugwu & Mbupu

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Ụlọ ọrụ anyị na ụlọ ọrụ mmepụta ihe

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