Ịchọta uru ahụike nke Apigenin: Ụzọ Eke Maka ịdịmma

Apigenin bụ ngwakọta flavonoid sitere n'okike nke dị n'ụdị osisi dị iche iche n'ụdị pigmenti odo odo.

Apigenin (Apigenin-Shanghe Biology) sitere na celery osisi umbelliferous, a na-ahụkwa ya na osisi ndị ọzọ dị ka chamomile, melissa, perilla, verbena, na yarrow. Chamomile bụ nwa afọ England ma na-akọ na Germany, France na Morocco. Roman chamomile na German chamomile na-ekerịta ọtụtụ njirimara: ihe dị ka 30 cm n'ogologo, nwere etiti edo edo, ifuru na-acha ọcha, na obere ntutu. Chamomile nwere mmetụta nke na-enyere aka ihi ụra, na-ebelata mbufụt nke onye ọrịa na mgbaàmà mgbu, na-ebelata ehighị ụra nke ọma n'ihi itching akpụkpọ anụ ahụ. Enwekwara nnukwu ihe ọkụkụ na China, nke a na-eji dị ka ọgwụ na tii. Apigenin na-etinye n'ime ihe ndị a na-ere ọgwụ herbal teas kwa ụbọchị, tumadi site na okooko osisi a mịrị amị nke matricaria chamomile.

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Gịnị bụ Apigenin ?

Enwere ike ịsị na Apigenin bụ ahịhịa celery ọhịa, na protein ọdịnaya nke akwụkwọ ya agafeela nke ọma celery anyị na-eri. Apigenin, nke a makwaara dị ka apigenin, bụ ihe polyphenolic na ihe bioflavonoid nke anyị nwere ike ịhụ na osisi dị iche iche. Mmetụta nke apigenin dị nnọọ ukwuu karịa nke celery anyị. Ihe ndị na-edozi ahụ nwere ike gboo mkpa ahụ mmadụ, a pụkwara ikwu na ọ na-enye aka na ahụ ike. Ọ bụrụ na ọ ga-ekwe omume, onye ọ bụla ga-agarịrị chọpụta ma kpọtụrụ ya.

Uru nri na nrụpụta apigenin

1. Ọdịnaya nke mineral na vitamin dị na apigenin buru ibu, ya mere apigenin nwere mmetụta dị iche iche nke antioxidant. Apigenin bụkwa onye na-ahụ maka ion ion metal, nke nwere ike ibelata ikere òkè ya na mmeghachi omume radical free site na chelating metal ion, si otú ahụ belata na igbochi ọgbọ nke oxygen free radicals, na nwere ike igbochi lipid peroxidation. Apigenin nwekwara ike ichebe obi anyị ma chịkwaa ọbara mgbali anyị.

2. Apigenin Dị ka aha ahụ na-egosi, anyị nwere ike wepụ ihe a na celery. Nnyocha e mere egosiwo na ọdịnaya apigenin dị na akwụkwọ celery ji okpukpu abụọ karịa nke mgbọrọgwụ celery, yabụ gbalịa ka ị ghara ịtụfu akwụkwọ celery mgbe ị na-eri celery. Ọtụtụ mgbe, onye ọ bụla ga-ewepụ akwụkwọ celery ma rie naanị akụkụ mgbọrọgwụ nke celery. N'ezie, nke a bụ ihe efu na ọ bụghị ihe na-edozi ahụ. Onye nchịkọta akụkọ ahụ amachaghị banyere okwu apigenin mbụ, amụtakwara m ya na mberede, ya mere m ga-agwa gị taa, ka onye ọ bụla nwee ike ịghọta. Amaghị m ma ọ bụrụ na onye ọ bụla nwere ntakịrị nghọta nke apigenin mgbe ọ gụchara isiokwu a. Ị ga-atụle iri akwụkwọ celery mgbe ị na-eri celery n'ọdịnihu? N'ezie, uru nri nke celery dị oke elu. Ọ ga-amasị m ịtụ aro na ndị na-adịghị amasị iri celery nwere ike ịnwale ya.

Uru ọgwụ apigenin :

Apigenin bụ ụdị flavonoids, apigenin nwere ike igbochi mmụba nke mkpụrụ ndụ akwara dị nro, si otú a gbochie ọbara mgbali elu, arteriosclerosis, ọrịa obi na akwara ozi. Apigenin nwere mmetụta antioxidant, nwere ike ibelata ọgbọ nke oxygen free radicals, na-egbochi mmeghachi omume lipid peroxide, na-egbu oge ịka nká nke ahụ mmadụ. Apigenin nwere ike igbochi uto mkpụrụ ndụ tumo, na-egbochi metastasis tumor, ma nwee mmetụta mgbochi tumor. Apigenin nwere ike daa jụụ, melite ebe nchekwa, melite ụra ma kwalite ikike mmụta.

Njirimara anụ ahụ na nke kemịkal :

kristal agịga odo (pyridine aqueous solution), mp.345℃~350℃. Ọ fọrọ nke nta ka ọ bụrụ ihe a na-adịghị ahụkebe n'ime mmiri, ma na-adị mfe nro na ethanol na-ekpo ọkụ, soluble na ngwọta potassium hydroxide KOH. Apigenin nwere diuretic, usoro ọbara mgbali elu, antibacterial, mgbochi mkpali na mmetụta ndị ọzọ.

Isi iyi osisi :

Apigenin (Apigenin) bụ ihe sitere n'okike nke flavonoid, nke dị n'ụdị osisi dị iche iche n'ụdị pigmenti odo odo, nke sitere na celery nke osisi Umbelliferae, na osisi ndị ọzọ dị ka chamomile, melissa, na perilla Ọ bụkwa ya. achọtara na , verbena, na yarrow. Chamomile bụ nwa afọ England ma na-akọ na Germany, France na Morocco. Roman chamomile na German chamomile na-ekerịta ọtụtụ njirimara: ihe dị ka 30 cm n'ogologo, etiti odo odo, okooko osisi na-acha ọcha, obere akwụkwọ ntutu. Chamomile nwere mmetụta nke na-enyere aka ihi ụra, na-ebelata mbufụt nke onye ọrịa na mgbaàmà mgbu, na-ebelata ehighị ụra nke ọma n'ihi itching akpụkpọ anụ ahụ. Enwekwara nnukwu ihe ọkụkụ na China, nke a na-eji dị ka ọgwụ na tii. Apigenin na-etinye n'ime ihe ndị a na-ere ọgwụ herbal teas kwa ụbọchị, tumadi site na okooko osisi a mịrị amị nke matricaria chamomile. Xiaonan deziri ozi dị n'elu site na Chemicalbook. Ọrụ ndu na mmetụta ọgwụ ọgwụ Ọdịdị molekụla nke apigenin na-ekpebi mmetụta physiological pụrụ iche ya na njirimara ndu, yana ọ nwere mmetụta dị mma. Ọnụ ọgụgụ dị ukwuu nke ọmụmụ n'ụlọ na ná mba ọzọ achọpụtala na apigenin bụ antioxidant sitere n'okike, nke nwere ike belata ọbara mgbali elu ma mee ka arịa ọbara dị jụụ, gbochie atherosclerosis, igbochi tumor na ihe ndị ọzọ. E jiri ya tụnyere flavonoids ndị ọzọ (quercetin, kaempferone), ọ nwere njirimara nke nsi dị ala na enweghị mutagenicity. Ka ọ dị ugbu a, apigenin nwere ụfọdụ ngwa na ọgwụ, nri na ụlọ ọrụ ndị ọzọ. Otú ọ dị, n'ihi na-adịghị mma mmiri solubility na eriri afọ absorption nke apigenin, ya onu bioavailability dị ala na ọrụ ya na vivo dị ala, nke na-egbochi ngwa ya ruo n'ókè ụfọdụ.

Chemical Njirimara :

Ọ fọrọ nke nta ka ọ bụrụ ihe a na-adịghị ahụkebe na mmiri, nke na-agbaze na ethanol na-ekpo ọkụ, soluble na ngwọta KOH. Nke sitere na celery ApiumgraveolensL.var.dulceDC.

Iji :

flavonoids, nke nwere ike weghara usoro G2/M nke okirikiri cell ma gbochie mgbasawanye cell. Na-egbochi uto, na-ebute apoptosis, ma jiri ya mee ihe dị ka ọgwụ tumor. Ihe eji eme ihe flavonoids dị na apigenin bụ ụdị flavonoids osisi, nke achọpụtara na ọ na-egbochi mgbasa mkpụrụ ndụ site na ijide okirikiri cell n'oge G2/M. Mgbochi nke uto site na njide okirikiri cell na ntinye nke apoptosis yiri ka ejikọtara ya na ntinye nke p53. Na-egbochi nkwalite tumor mgbasa ozi PMA site na mgbochi nke protein kinase C na nkwụsị nke nkwupụta oncogene. Nnyocha egosiwokwa mgbochi nke topoisomerase I-catalyzed DNA rejoining na nkwalite nke oghere njikọ cell-na-cell nkwurịta okwu.

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