Chọpụta uru ahụike nke Gypenoside: Ngwa Ebube nke okike

Gynostemma Pentaphglum(Thunb) Makino bụ ahịhịa ahịhịa nke ezinụlọ cucurbit. N'ihi uto ilu ya, a na-akpọkwa ya bile akwụkwọ asaa na ndị mmadụ. Ewebata site na Japan maka ụdị ụtọ, nke a makwaara dị ka osisi vine dị ụtọ. Ọ bụ ụdị ọgwụgwọ ọdịnala na nke dị oké ọnụ ahịa nke ndị China, nke nwere ogologo akụkọ ihe mere eme nke ngwa n'asụsụ Chinese, ma e bipụtara ya na mbụ na Ming Dynasty, na Tang Materia Medica, Compendium nke Materia Medica na akwụkwọ nkà mmụta ọgwụ ndị China ndị ọzọ a ma ama na-edekọ. n'ụzọ zuru ezu.

Akụkụ bụ isi na-arụ ọrụ nke gypenoside bụ gypenoside. Ebe ọ bụ na ọkà mmụta Japan Nagai et al. panaxanediol dịpụrụ adịpụ na ZX-hydroxypanaxanediol na 1976, 83 saponins, ndị a na-akpọkarị gypenosides, kewapụrụ ma wepụta ya na nyocha mmadụ na gynostemma gypenosides, bụ nke sitere na nhazi nke dalma fatty anols. N'ime ha, gypenosides 3,4,8,12 na ginsenosides Rb1, Rb3, Rd, F2 bụ otu n'ime usoro kemịkalụ, na ndị ọzọ nwere ike iwere dị ka protopanaxanediol ma ọ bụ panaxantriol isomers. Enwere ike nweta Gypenoside K site na enzymolysis nke gypenoside 1-16, gypenoside V-AH bụ otu ihe ahụ dị ka ginsenoside Rg3, nke ọdịnaya nke gypenoside 8 bụ ugboro 8 nke ginsenoside Rd, na mkpokọta saponin dị okpukpu atọ nke ginseng. . Site na ọmụmụ ihe gbasara ọgwụ, egosila na gypenoside nwere mmetụta adaptogenic nke ginseng ma bụrụ onye nnọchi anya siri ike. N'otu oge ahụ, ọ nwere mgbochi ọrịa cancer, mgbochi ọnya, mgbochi lipemia, sedation, mgbochi ike ọgwụgwụ na ogologo ndụ cell, n'ihi ya, a maara ya dị ka "n'ebe ndịda ginseng" aha. Na mgbakwunye, Gypenoylum nwekwara flavonoids, sugars na ọtụtụ amino acid dị mkpa maka ahụ mmadụ, vitamin na ihe ndị dị mkpa dị ka selenium, zinc, iron, manganese.

Dabere na ọrụ nlekọta ahụike dị mkpa nke gynostylus gibbosa na ahụ mmadụ, nyocha ngwa nke gynostylus gibbosa n'ụlọ na mba ọzọ na-etowanyewanye, a na-ejikwa ya na ihe ịchọ mma, nri, ngwaahịa nlekọta ahụike, ọgwụ na ụlọ ọrụ ndị ọzọ.

"Laghachi na ọdịdị" bụ okwu izugbe nke ụlọ ọrụ ịchọ mma mba ụwa ugbu a, na mba ndị dị elu na-etinye nnukwu mkpa na mmepe nke ịchọ mma eke. N'okwu a, a na-akwado ọgwụgwọ ahịhịa nke China, egosighi amara ya pụrụ iche, ma na-arụ ọrụ na-enweghị atụ na ụlọ ọrụ ịchọ mma. N'ihi ọrụ ya dị ukwuu ma dị ịrịba ama, gynostylus na-adọta mmasị nke ndị na-emepụta ihe ịchọ mma.

Mmetụta arụ ọrụ nke gynostaphyllus na akpụkpọ ahụ mmadụ na-egosipụtakarị n'akụkụ ndị a:

1. Mgbochi ịka nká mmetụta. Ọtụtụ mgbe, mgbe ntụpọ afọ (nke a na-akpọkwa lipofuscin) na ntụpọ aja aja na freckles na-etolite, lipid peroxide nwere ike ịhụ n'ọtụtụ buru ibu na akpụkpọ ahụ wee mụbaa. Mgbe ndị mmadụ na-eto eto, ike decompose na excrete lipid peroxide na-esi ike, na mmetụta nke a ji nwayọọ nwayọọ na-ebelata ka afọ, na-akpata ịka nká nke akpụkpọ cell.

Mkpokọta saponins nke gypenoside nwere ike belata ma gbochie mmepụta nke lipid peroxide, chebe akpụkpọ ahụ akpụkpọ ahụ site na mmebi, ma gbochie senescence cell. Nsonaazụ gosiri na mkpokọta saponins nke gypenosides nwere ike ịgbatị ndụ cell nke fibrocytes diploid nwa ebu n'afọ na mkpụrụ ndụ akpụkpọ anụ Verner. Na omenala vitro nke mkpụrụ ndụ akpụkpọ anụ mmadụ, na-agbakwụnye usoro omenala nke 0.2% gypenoside, mkpụrụ ndụ nwere ike ịgafe site na ọgbọ 22 ruo ọgbọ 27, ya bụ, ogologo ndụ nke mkpụrụ ndụ nwere ike ịgbatị 22.7%, ya mere gypenoside nwere mmetụta na-arụ ọrụ. na akpụkpọ cell na ike mee ngwa ngwa akpụkpọ

Mweghachi nke mkpụrụ ndụ elu, na-egbu oge ịka nká anụ ahụ. Mmetụta mgbochi ịka nká nke Gypenoch na ahụ bụ n'ihi na ọ nwere ike ịbawanye ọrụ nke enzymes antioxidant dị ka superoxide dismutase (SOD) n'ime ahụ mmadụ na sel epidermal akpụkpọ ahụ, na-ewusi mkpochapụ nke radicals free oxidation na-arụ ọrụ, na meziwanye metabolism nke ahụ.

2. Meziwanye microcirculation anụ ahụ. Nnwale ahụ gosipụtara na mkpokọta glucoside nke gypenoside nwere ike imeziwanye microcirculation nke akpụkpọ ahụ nke ọma, na mgbasa ọbara nke akpụkpọ ahụ jupụtara, na akpụkpọ ahụ na-egbuke egbuke ma na-egbuke egbuke.

3. melite nguzogide akpụkpọ ahụ, gbochie mkpụrụ ndụ akpụkpọ ahụ ịghọ ọrịa kansa. Nnwale na-egosi na mkpokọta glucoside nke gypenoside nwere ike imezi ihe nchebe nke ahụ ma gbochie ọrịa akpụkpọ ahụ. Omenala cell gosipụtara na mkpokọta glucoside nke gypenoside nwere ike igbochi ọrịa kansa cell, na ọnụ ọgụgụ igbu egbu nke mkpụrụ ndụ etuto dị elu dị ka 91%. Ya mere, ọ nwere ike ichebe akpụkpọ ahụ ma gbochie ọrịa cancer anụ ahụ.

Gypenoside nwere ụdị ginsenosides dị iche iche, nke nwere ike ịkwalite mmebi nke cutin akpụkpọ anụ dị ka ginseng; Mgbasa na metabolism nke sel oyi akwa germinal epidermal; Akpụkpọ ahụ collagen fiber mmeghari ohuru, nhazi nhazi na ọrụ ndị ọzọ nwere ike ime ka akpụkpọ ahụ dị nro ma na-agbanwe. Na mgbakwunye na ginseng saponins, Gypenoside nwekwara amino acid dị iche iche, vitamin na ihe ndị na-achọpụta ihe, nke na-emekọrịta ihe na-eme ka akpụkpọ ahụ dị nro, nwere ike iwepụ ntụpọ gbara ọchịchịrị, gbochie akpụkpọ ahụ siri ike.

Mmebi mgbochi ultraviolet, mgbochi ike na mmetụta creasing. Ìhè anyanwụ, ultraviolet ìhè, ozone, nitrogen oxides na ọtụtụ ụlọ ọrụ mmetọ kpaliri ọgbọ nke oxygen radicals na-arụ ọrụ, nke butere oxidation nke sulfhydryl otu melanocytes akpụkpọ ma ọ bụ mụbaa ozugbo ọrụ coolinase. Radieshon okpomọkụ nwekwara ike ịbawanye mmeghachi omume tyrosine-tyrosinase, nke mere na melanin akpụkpọ ahụ na-abawanye, akpụkpọ ahụ na-agba ọchịchịrị; Mmụba nke melanin n'ime mpaghara nwere ike ibute ntụpọ ojii ma ọ bụ nchara nchara. Nnwale egosila na ihe ịchọ mma nwere gypenoside dị ka ihe na-arụ ọrụ nwere ike iguzogide mmetụta ultraviolet na ìhè anyanwụ na akpụkpọ ahụ, gbochie ịcha akpụkpọ anụ, ma belata ma ọ bụ ọbụna na-agbaze ntụpọ ojii na agba aja aja. Na mgbakwunye, mkpokọta glucoside nke gypenoside nwere mmetụta nke mgbochi ike na mgbochi mgbawa, wee rụọ ọrụ abụọ nke ịma mma na nlekọta ahụike.

6. Mee ka mmụọ nsọ guzosie ike ma gbochie mmetụta ọjọọ. Nsogbu uche, oke obi ụtọ, ezumike na-adịghị mma, tinyere ike ọgwụgwụ, ga-eduga n'ọgba aghara nke anụ ahụ, na-eme ka ndị mmadụ na-agba agba, akpụkpọ ahụ na-efunahụ na elasticity, na-adịkarị ka wrinkles, na-apụta ochie. Glucoside ngụkọta nke gypenoside nwere ọrụ nke ime ka mmụọ guzosie ike, na-ebelata esemokwu na ike ọgwụgwụ, nke nwere ike ime ka ndị mmadụ nweta ume, ihu na-acha uhie uhie, ọ dịghị mfe ịmepụta wrinkles, na-apụta na-eto eto na ike.

7. The hydrophilic mejupụtara nke gypenoylum nwere ike budata igbochi mmepụta nke free ọdụdụ asịd na njikọ nke na-anọpụ iche abụba site abụba mkpụrụ ndụ, na-egbochi ntughari nke glucose n'ime abụba, n'ihi ya, ọ nwere ike na-ekere òkè na ibu ọnwụ site ụkpụrụ nke abụba metabolism. .

Oke oke ibu nke mmadụ abụghị mmụba nke mkpụrụ ndụ abụba, mana mmụba nke oke abụba subcutaneous n'ihi mmụba nke mkpụrụ ndụ abụba. A tụrụ ọnụọgụ nke pulses kwa nkeji (CPm) nke adipocytes mgbe adipocytes na tracer compound C14-glucose mebere na 37 ℃ maka ọkara otu awa, na index nke glucose na-abanye n'ime sel iji mepụta abụba na-anọpụ iche. Ọnụ ọgụgụ nke CPm tụrụ kwa gram nke adipocytes bụ naanị ihe dịka 50% nke na-abụghị nke agbakwunyere. Ọ na-egosi na ihe mejupụtara hydrophilic nke gynostaphyllum nwere ike igbochi njikọ nke abụba na-anọpụ iche site na mkpụrụ ndụ abụba, belata nha nke sel abụba, ma si otú ahụ nwee mmetụta nke ọnwụ. Oral gyro blue bodybuilding mbadamba (mbadamba nke hydrophilic Efrata) belata abụba njikọ si n'ozuzu anya, na mpaghara ngwa nwere ike ime ka ọgwụ ozugbo eme ihe na ọkpụrụkpụ nke subcutaneous abụba, si otú na-egwu a arọ ọnwụ, bodybuilding mmetụta.

A na-eji Gypenoside na-asa ntutu na ngwaahịa nlekọta ntutu isi, ma nwee ọrụ ndị a:

1. Mma microcirculation ntutu, mee ka epidermal germinal oyi akwa cell metabolism ike, akpụkpọ collagen fiber mmeghari na nkwalite, na ike igbochi ntutu isi n'isi ọcha na-emeso senile alopecia. Nnyocha egosiwo na gynostemus nwere ike ibelata ntutu isi ọcha n'oge agadi site na 80% ruo 50%, 40% ruo 25%, na 25% nke ntutu isi ọcha nwere ike ịbụ oji niile mgbe otu afọ gasịrị.

2. Na-egbochi senescence cell na ogologo ndụ cell. Mwube nke mkpụrụ ndụ akpụkpọ anụ nwụrụ anwụ na-etolite dandruff. Mmetụta mgbochi ịka nká nke gypsetonin nwere ike ịgbatị ndụ mkpụrụ ndụ akpụkpọ anụ, belata ọgbọ nke dandruff, ma nwee ọrụ nke antiseptik na antipruritic.

3. mmebi mgbochi UV, na-edozi ntutu isi. Ọ nwere ike igbochi ntutu isi ka ọ ghara ịdị na-acha odo odo na nke siri ike n'ihi ifufe na anyanwụ, ma na-enyere aka n'ịrụzi mmebi ntutu kpatara site na igwe eletriki, igwe oyi, agba ntutu, wdg. nro.

Tụkwasị na nke ahụ, gypenoside nwere ọrụ elu dị mma, ike ịfụ ụfụ siri ike, emulsification, mgbasa ozi, wetting na ihe ndị ọzọ, na ịsacha na nsị dị mma, ya mere ọ bụ ihe magburu onwe ya na-emepụta ihe ndị dị ndụ.

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