Sulforaphane ntụ ntụ nnukwu

Kedu ihe bụ sulforaphane?

Sulforaphane ntụ ntụ nnukwu, nke a makwaara dị ka "sulforaphane", dị ukwuu na osisi cruciferous dị ka broccoli, kale, na carrots ugwu. Ọ bụ ihe na-eme ka ọ bụrụ ihe na-eme ka ọ bụrụ ihe na-eme ka ọ bụrụ ihe na-eme ka ọ bụrụ ihe na-eme ka ọrịa cancer dị ike ma dị irè. Ihe kacha arụ ọrụ kacha mma. Ọ bụ inducer multifunctional nke nwere ike ime ka anụ ahụ mepụta ụdị II detoxification enzymes - glutathione transferase na quinone reductase. Enzyme a nwere ike imepụta iguzogide ọtụtụ carcinogens ma gbochie carcinogens ibibi ihe mkpụrụ ndụ ihe nketa na sel ahụike.

Sulforaphane buru ibu bụ isothiocyanate, nke a na-enweta site na hydrolysis nke glucosinolates (Glu, nke a na-akpọ glucosinolates) site na myrosinase enzyme na osisi. Usoro ihe omimi bụ C6H11NOS2. Ọ dị ukwuu na osisi cruciferous dị ka broccoli, kale, na carrots ugwu. Ọ bụ ihe na-emekarị antioxidant na ihe ọkụkụ na-arụ ọrụ nke nwere mmetụta kachasị mma na-egbochi ọrịa cancer nke dị na akwụkwọ nri.

Olee uru?

1. Na-akpali mmepụta nke II enzyme

Sulforaphane ntụ ntụ nnukwu na-ebute mmepụta nke ụdị II na-emebi enzymes na mkpụrụ ndụ mmadụ ma ọ bụ anụmanụ ma na-egbochi mmepụta nke ụdị nke I. Usoro ihe omume ya bụ: igbochi ụzọ metabolic chọrọ maka carcinogens iji mepụta mmetụta carcinogenic, igbochi carcinogens ma ọ bụ metabolites ha ịbanye n'ime sel ezubere iche, na n'otu oge ahụ wepụ carcinogens; na-egbochi nkewa cell na uto, igbochi ụzọ mgbasa ozi; na-akwalite Protein ndị ọzọ na-egbu mkpụrụ ndụ ka e zoro ezo iji gbochie mmetụta ndị na-ebute ọrịa kansa nke carcinogens.

2. Na-alụ ọgụ mbufụt nke afọ ma melite usoro nri nri

Ọ bụ ezie na microorganisms ole na ole nwere ike ịdị ndụ na gburugburu acidic na hypoxic nke afọ anyị, Helicobacter pylori bụ ihe pụrụ iche. Ọ nwere ike ịkpata mbufụt nke afọ anyị na-adịghị ala ala, ọbụnakwa bute ya ọnya. Ugbu a, ndị nchọpụta achọpụtala na sulforaphane ewepụtara na mkpụrụ osisi broccoli nwere ike ime ihe na nje a ozugbo, si otú a na-echebe mucosa eriri afọ nke ndị ọrịa ma belata mbufụt.

3. Mee ka ụbụrụ dị ike ma na-eguzogide ọrịa akwara ozi

Ndị ọkà mmụta sayensị si mba dị iche iche anọwo na-eme nchọpụta banyere irighiri akwara ụbụrụ ruo ogologo oge. N'oge a, a mụọkwara sulforaphane ka ọ nwee mmetụta bara uru na ụbụrụ, na ọmụmụ ndị a agbasawanyela n'ọtụtụ ọrịa akwara ozi, dị ka ọrịa Alzheimer (AD), ọrịa Parkinson, ọrịa Huntington, na ọrịa amyotrophic mpụta. Sclerosis, multiple sclerosis, autism ụdịdị dị iche iche ọrịa, na schizophrenia. Na ụfọdụ ọmụmụ izizi egosila na sulforaphane nwere mmetụta neuroprotective dị iche iche na AD pathophysiology.

Kesaa

Achọpụtala ihe karịrị ụdị glucosinolates 120 n'ime osisi. A na-achọta ọdịnaya kachasị elu nke glucosinolates na mkpụrụ osisi cruciferous. A na-ekesa ya n'akụkụ niile nke osisi ahụ, karịsịa na mkpụrụ osisi. A ga-emetụta ọdịnaya glucosinolate dị na osisi site na gburugburu ebe uto nke mpụga, ya mere ọdịnaya sulforaphane ga-emetụtakwa ọnọdụ gburugburu ebe obibi. Osisi dị iche iche nwere ọdịnaya glucosinolate dị iche iche. N'ozuzu, ọdịnaya glucosinolate dị na akwụkwọ nri Brassica bụ 500 ~ 2 000 μg · g-1, n'ime nke broccoli nwere ọdịnaya kachasị elu, karịsịa na mkpụrụ na mkpụrụ osisi. Ọdịnaya glucosinolate bụ nke kachasị na akwụkwọ nri tozuru oke. 10 ruo 100 ugboro nke osisi. Ya mere, broccoli bụ ezigbo akụrụngwa maka iwepụta sulforaphane.

Nnyocha na-egosi na a na-ahụkarị sulforaphane n'ime akwụkwọ nri cruciferous. Akụkụ oriri nke ụdị inine cruciferous 9 akpọnwụwo n'okpuru nrụgide nkịtị na okpomọkụ atọ dị iche iche nke 50C, 70C na 90C, na sulforaphane ha nwetara site na HPLC. Nsonaazụ gosiri na ọdịnaya sulforaphane n'ime akwụkwọ nri cruciferous itoolu bụ n'usoro nke Brassica> Radish; N'etiti ụdị Brassica, broccoli nwere ọdịnaya sulforaphane kachasị elu na 480 μg.g-1, kọlịflawa nwere ọdịnaya kachasị dị ala na 35.2 μg.g. -1; n'etiti radish genus, karọt nwere sulforaphane kachasị elu, nke bụ 80.9 μg.g-1, na radish ọcha nwere ọdịnaya kachasị ala, nke bụ 19.8 μg.g-1; na ọgwụgwọ nke otu sample na atọ dị iche iche ihicha okpomọkụ, 90 Nke kasị elu sulforaphane ọdịnaya na sample akpọnwụwo na ℃.

Ntuziaka ngwa

Sulforaphane dị ọcha egosila na ọnụ ọgụgụ dị ukwuu nke ọmụmụ ụlọ na nke mba ọzọ nwere uru ọgwụ na ike dị oke elu, a na-ejikwa ya n'ọhịa nke ọgwụ na ngwaahịa nlekọta ahụike.

Sulforaphane dị ọcha na-ebu

Yuantai Organic Bio na-agba mbọ inye ndị ahịa ihe kacha mma Sulforaphane ntụ ntụ nnukwu na ọrụ ka onye ọ bụla na-azụ ahịa nwee ike ịnụ ụtọ nri eke, ahụike yana oke mma. Ọ bụrụ na ị nwere ajụjụ ọ bụla ma ọ bụ mkpa gbasara ngwaahịa anyị, biko nweere onwe gị ịkpọtụrụ anyị, anyị ga-azaghachi gị ozugbo enwere ike.

Ngwugwu & Mbupu

Ụlọ ọrụ anyị na ụlọ ọrụ mmepụta ihe