Gardenoside

CAS: 24512-63-8
Usoro ihe omimi: C17H24O10
Ibu ibu: 388.37
Ebe mgbaze: 160.0 ruo 164.0 Celsius
Ebe esi esi: 641.4 ± 55.0 Celsius C (buru amụma)
Njupụta:1.54±0.1 g/cm3(buru amụma)
Mbupu ọsọ: 1-3 ụbọchị
Ngwaahịa: Ọ dị na ngwaahịa
Asambodo: HACCP, HALAL, KOSHER, ISO9001, ISO22000, FDA
MOQ: 25KG
Ngwugwu: 25kg / gbọmgbọm
Ndị na-ere ahịa: ọ bụghị maka ndị ahịa ọ bụla

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Kedu ihe bụ gardeniposide?

Ọ bụ ngwakọta organic nke nwere usoro ihe omimi C17H24O10. A na-ewepụta ma nụchaa ngwaahịa a site na mkpụrụ osisi mịrị amị na tozuru oke nke osisi Rubiaceae Gardenia site na iji teknụzụ mmepụta teknụzụ dị elu. Ọ bụ ogige iridoid glycoside nwere aha geniposide, geniposide na dehydroxygardeniposide. Ngwaahịa ahụ dị ọcha bụ ntụ ntụ na-acha ọcha nwere ntụgharị ntụgharị [α]D20+7.5° (mmiri). Na-agbaze ngwa ngwa n'ime mmiri, soluble na ethanol, nke na-adịghị edozi na ether petroleum. Ọ nwere ihe eji eme ihe dị iche iche ma nwee ike ịgba ọkụ n'okpuru ọnọdụ dị iche iche iji mepụta colorants eke eri nri gardenia blue na gardenia red. Ọ bụkwa ọgwụ akụrụngwa eji agwọ ọrịa obi, cerebrovascular, hepatobiliary na ọrịa ndị ọzọ yana ọrịa shuga.

Ọ bụ nnukwu iridoid glycoside ewepụtara na ọgwụ ọdịnala ndị China Gardenia. Ọ nwere ọtụtụ uru bara uru dị ka ọrịa mgbochi obi, mgbochi mkpali, mgbochi ọrịa shuga, mgbochi skeletal muscle fibrosis, neuroprotection, hepatoprotective, choleretic, na hypolipidemia. Ọrụ. A maghị ma hypercholesterolemia nwere ike imeziwanye ya site n'ịgbanwe metabolism nke bile acid na ụmụ oke. Iji mezuo nke a, ndị otu ahụ mere ọtụtụ nyocha, nyocha ahụ gosipụtara nke ahụ gardeniposide na-achịkwa metabolism nke cholesterol site na ịhazi FXR-mediated hepato-intestinal crosstalk nke bile acids, si otú ahụ na-arụ ọrụ mgbochi atherosclerotic ya ma na-enye ntọala ọhụrụ maka atherosclerosis na atherosclerosis. Ọrịa obi obi na-enye usoro ọgwụgwọ ọhụrụ.

gardeniposide

Olee uru?

mmetụta hypoglycemic

 Nnwale anụmanụ ekwenyela na dịka isi ihe na-arụ ọrụ nke gardenia, ọ nwekwara mmetụta dị mma n'igbochi na ịgwọ ọrịa shuga. Usoro ya metụtara ichekwa mkpụrụ ndụ beta nke pancreatic, na-arụ ọrụ peroxisome proliferator-activated γ (PPARγ) na glucagon-dị ka peptide 1 (GLP-1).


Mee ihe nnabata PPARγ rụọ ọrụ

A na-egosipụta PPARγ na anụ ahụ adipose ma na-echebe ahụ ike, imeju na sel pancreatic β-cell site na mmetụta nke nnukwu abụba abụba n'efu site n'ịbawanye nnabata na nchekwa nke fatty acids n'efu na anụ ahụ adipose.

Yan Jing'en et al. achọpụtara na gardeniposide nwere ike ịgbalite ma mụbaa ọrụ nke onye na-anabata proliferator γ (PPARγ), si otú a na-eme ka nzaghachi nke mkpụrụ ndụ ihe nketa ala na insulin, na-ebelata ibu nke insulin na-akwụ ụgwọ site na mkpụrụ ndụ beta nke pancreatic islet, ma na-ebelata metabolism nke agwaetiti. β-cell apoptosis, si otú a na-egbochi mgbanwe na mmepe nke ụdị Ⅱ ọrịa shuga ka pịnye Ⅰ multi-organ ọdịda ọrịa shuga.


glucagon-dị ka peptide-1 ụzọ mgbaàmà nnabata

Glucagon-dị ka peptide-1 (GLP-1), isi mmetụta anụ ahụ ya gụnyere ịba ụba insulin na-adabere na glucose na igbochi mwepụta glucagon, si otú ahụ na-egosipụta mmetụta hypoglycemic ya dị mma.

Ọ nwere ike ịkwalite secretion insulin site na ịgbalite ụzọ mgbama glucagon-dị ka peptide-1, si otú a na-ebelata shuga ọbara ma na-emeziwanye ihe mgbaàmà nke ọrịa metabolism lipid. Nnyocha egosiwo na iridoid gardeniposide bụ GLP-1 agonist nnabata site na nyocha dị elu, yana gardeniposide nwere ọrụ neurotrophic na neuroprotective yiri ya. Akụkọ nyocha ndị ọzọ egosila na ndị na-anabata glucagon-dị ka peptide 1 na-arụ ọrụ dị mkpa na sel INS-1 na-achịkwa secretion insulin site na gardeniposide. Mee GLP-1R rụọ ọrụ, wee mezie mkpokọta Ca2+ ma ọ bụ gbanwee nguzozi ike nke ike site na ụzọ akara, ya bụ, gbanwee oke ATP, wee na-ahazi ọrụ ọwa ATP nwere mmetụta K+.


Ọ nwere mmetụta nchebe na neurons mebiri site na cerebral ischemia, na ụzọ isi eme ya bụ ịkwalite astrocytes na sel ndị ọzọ iji mepụta ihe na-eto eto fibroblast (bFGF). Ndị nchọpụta ndị ọzọ achọpụtala na gardeniposide na ihe dị iche iche dị na gardenia wepụ nwere ogo dị iche iche nke nchebe nchebe na mmebi nrụgide endothelial cell oxidative, na ka ọdịnaya na-abawanye, mmetụta nchebe oxidative na-eme ka ọ dịkwuo ogo dị iche iche. Nke a na-egosi na enwere njikọ pharmacodynamic dị n'etiti gardeniposide na gardenia na mmetụta nchebe nke mkpụrụ ndụ endothelial megide nrụgide oxidative. Tụkwasị na nke ahụ, ọ nwekwara ike ịmepụta mmetụta nchebe ụfọdụ site n'ibelata ọrụ cyclooxygenase-2 (COX-2) na 5-lipoxygenase (5-LOX) na ụbụrụ ụbụrụ mgbe ụbụrụ ụbụrụ ụbụrụ na-emegharị. Mbelata ọdịnaya nke monocyte chemoattractant protein-1 (MCP-1) na ụbụrụ ụbụrụ mgbe ischemia gachara nwekwara ike ịbụ otu n'ime usoro nke gardeniposide n'ịgwọ ọrịa ischemia cerebral.

Ntuziaka ngwa

pigmenti

N'okpuru ọrụ β-glucosidase, gardenia glycoside na-enweta mmeghachi omume polymerization na amino acid bụ isi (glycine, lysine, na phenylalanine) na-etolite gardenia blue. Phycocyanin nke ewepụtara na gardenia blue na spirulina bụ naanị pigmenti na-acha anụnụ anụnụ abụọ dị ugbu a. Ngwongwo ha kwụsiri ike ma ejirila ya mee ihe n'ọtụtụ ebe.

nkà mmụta ọgwụ

Genipin a dịgasị iche iche nke ọgwụ mmetụta, dị ka hepatoprotective, choleretic, mgbochi mkpali, mgbochi thrombotic, mgbochi fibrosis, ọgwụgwọ nke ọrịa shuga na neurodegenerative ọrịa, wdg, karịsịa na mgbochi na ọgwụgwọ nke dị iche iche nnwale ọrịa imeju, o nwere. nwetakwuo anya. nlebara anya ma nwee atụmanya ngwa ahụike dị mma.

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Gardeniposide soplaya

Yuantai Organic Bio na-agba mbọ inye ndị ahịa ihe kacha mma nnukwu gardeniposide ntụ ntụ na ọrụ ka onye ọ bụla na-azụ ahịa nwee ike ịnụ ụtọ nri eke, ahụike yana oke mma. Ọ bụrụ na ị nwere ajụjụ ọ bụla ma ọ bụ mkpa gbasara ngwaahịa anyị, biko nweere onwe gị ịkpọtụrụ anyị, anyị ga-azaghachi gị ozugbo enwere ike.

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Ngwugwu & Mbupu

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Ụlọ ọrụ anyị na ụlọ ọrụ mmepụta ihe

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