Nnukwu Rutin ntụ ntụ

Kedu ihe bụ rutin?

Nnukwu Rutin ntụ ntụ, nke a makwaara dị ka rutin na vitamin P, nwere usoro ihe omimi nke C27H30O16. Ọ bụ flavonoid glycoside eke ma bụrụ nke flavonol glycosides nke dị na osisi. Abụọ glycosides bụ glucose na rhamnose. Ọdịdị: ìhè odo ma ọ bụ ìhè akwụkwọ ndụ akwụkwọ ndụ kristal ntụ ntụ. Soluble na pyridine, formyl na alkali, ntakịrị soluble na ethanol, acetone na ethyl acetate, ihe fọrọ nke nta ka ọ bụrụ ihe na-adịghị ike na chloroform, ether, benzene, carbon disulfide na ether petroleum. Ọ nwere mgbochi mkpali, antioxidant, mgbochi allergies, mgbochi nje na mmetụta ndị ọzọ.

Rutin ntụ ntụ bụ rutin glycoside nke flavonol compound quercetin. Ọ bụ ngwakọta flavonoid ewepụtara na osisi. A na-achọta ya na rue, buckwheat tartary, sophora buds, catalpa leaves, tomato ị ga, epupụta na mkpuru osisi. Ọ na-achọ ịma ifuru. Buckwheat kpọrọ nkụ ugbu a nwere ihe dịka 3%, na jujube, hawthorn, ginkgo, wolfberry, motherwort, bupleurum, prunella vulgaris, aloe, Gynostemma pentaphyllum, wdg niile nwere rutin. Na ifuru buds nke legume Sophora japonica L., ọdịnaya nwere ike iru karịa 20%, na ọ bụ isi akụrụngwa maka amịpụta rutin na mba m ụlọ ọrụ ọgwụ. Enwere ike imebi Rutin site na ịgbakwunye mmiri mgbe ị na-ezute acidity siri ike na alkalinity. Agba anaghị akwụsi ike na nri alkaline ma nwee ikike antioxidant. Na ethanol, ọ nwere ike melite nguzogide ọkụ nke nkwadebe pigmenti ma gbochie nkwụsị nke nta nke nta ma ọ bụ mgbanwe nke ísì. Ejikọtara ya na vitamin E, wdg, ọ nwere ike melite ikike antioxidant ya.

Mmetụta mgbochi nke rutin na lipid peroxidation metụtara nkwalite ọrụ SOD n'ime ahụ yana nkwalite ikuku oxygen n'efu. Xia Weimu na ndị ọzọ chọpụtara na rutin nwere mmetụta na-ekpo ọkụ siri ike na O2-, na arụmọrụ nke scavenging nwere ike iru karịa 96%. Dịka onye na-ahụ maka aghụghọ maka Fe2+, rutin nwere ike igbochi mmeghachi omume Fenton na mmeghachi omume yinye nke lipid peroxidation ma nwee mmetụta mgbochi lipid peroxidation doro anya. E mepụtala nri ahụike rutin dị iche iche na mba ofesi. Sophora osikapa nwere mmetụta antioxidant siri ike na mmanụ oriri. Ọnụego mkpochapụ n'efu nke Sophora japonica wepụ nwere ike iru 40% ruo 70%. Enwere ike iji ya dị ka ụdị ọhụrụ mmanụ oriri na ihe mgbakwunye nri nwere abụba nwere ọrụ nlekọta ahụike. A pụkwara iji ya na ihe ọṅụṅụ oyi, ihe ọṅụṅụ, pastries, na ngwaahịa anụ a na-edozi. , ngwaahịa mmiri emechara. Ihe ahụike Tartary buckwheat rutin nwere mmetụta nke iwetulata lipids ọbara, ibelata ọbara mgbali elu, ibelata shuga mmamịrị, na ifelata na ịdị mma. Emebela ya ka ọ bụrụ nri nri na-atọ ụtọ ma dị mma (tii buckwheat tartary, osikapa buckwheat tari, osikapa buckwheat tatarị, wdg). Hydrolyze rutin na 2% itughari H2SO4 maka awa 1, nyochaa ma na-anakọta mmiri ozuzo mgbe ọ dị jụụ, saa na nkụ, na ngwaahịa crude nwere ike ịmegharị site na ethanol iji nweta ezigbo quercetin. Ọ bụrụ na agwakọta flavonoids ndị ọzọ dị ka quercetin na α-tocopherol ma ọ bụ catechin, enwere ike igosipụta mmetụta mgbakwunye.

Olee uru?

Mmetụta radical na-enweghị atụ

A na-ebelata mkpụrụ ndụ oxygen n'ụdị nke otu electrons na metabolism cell. ion O nke a na-emepụta site na mbelata electron nke mkpụrụ ndụ oxygen na-emepụta H2O2 na oke egbu egbu ·OH free radicals n'ime ahụ, si otú ahụ na-emetụta ịdị nro na ire ụtọ nke akpụkpọ ahụ na ọbụna na-eme ka uto nke akpụkpọ ahụ dịkwuo elu. Ogo nke ịka nká, na ịgbakwunye rutin na ngwaahịa ahụ nwere ike iwepụ ụdị oxygen na-emeghachi omume nke mkpụrụ ndụ na-emepụta. Rutin bụ ngwakọta nke flavonoid na antioxidant siri ike nke na-emebi radicals n'efu. Ọ nwere ike kwụsịtụ mmeghachi omume yinye nke free radicals, na-egbochi peroxidation nke polyunsaturated ọdụdụ asịd na ndu membranes, wepụ lipid peroxidation ngwaahịa, na-echebe ndu membranes na Iguzosi ike n'ezi ihe nke subcellular Ọdịdị na-arụ ọrụ dị mkpa na ahụ.

Anti-lipid peroxidation

Lipid peroxidation na-ezo aka usoro oxidation usoro nke oxygen free radicals na-arụ ọrụ na-awakpo polyunsaturated ọdụdụ asịd na ndu membranes. Site na nha na nyocha nke ọrụ SOD oke oke, ngwaahịa radical radical peroxidation ngwaahịa MDA na nnukwu ọdịnaya lipofuscin imeju, achọpụtara na rutin nwere mmetụta mgbochi na lipid peroxidation na oke awụsara. Mbelata ikike antioxidant nke sistemu antioxidant oke oke. Rutin nwere ike igbochi mbelata nke ikike antioxidant kpatara mbelata nke estrogen endogenous ma nwee mmetụta antioxidant. Lipoprotein dị elu (HDL) nwere mmetụta antiatherosclerotic. Agbanyeghị, HDL, dị ka lipoprotein dị obere (LDL) na obere njupụta lipoprotein (VLDL), nwekwara ike gbanwee ya na vitro. Ozugbo HDL oxidized na gbanwee na Ox-HDL, ọ nwere mmetụta atherogenic. Meng Fang et al. ejiri Cu2+ -mgbasa ozi oxidative mgbanwe in vitro iji chọpụta mmetụta rutin na mgbanwe oxidative nke HDL. Nkwubi okwu na-egosi na rutin nwere ike igbochi mgbanwe oxidative nke HDL.

Na-emegide mmetụta nke ihe na-arụ ọrụ platelet

Ọrịa nke ọtụtụ ọrịa obi na ọrịa cerebrovascular, dị ka thrombosis, atherosclerosis, mmeghachi omume mkpali, na ischemia-reperfusion free radical mebiri, nwere njikọ chiri anya na mediation nke platelet activating factor (PAF). Ya mere, imegide mmetụta nke PAF bara uru na ọ bụ ugbu a ụzọ dị mkpa iji belata ọrịa obi na-arịa ọrịa obi na ọrịa cerebrovascular. Nnwale gosipụtara na rutin nwere ike itinye uche na-adabere na-emegide njikọ PAF kpọmkwem na ndị na-anabata membrane platelet, na-egbochi nnabata platelet nke oke bekee na PAF ma mee ka ntinye Ca2 + n'efu na PMNs, na-egosi na usoro nke rutin na-emegide PAF bụ site na igbochi PAF. A na-arụ ọrụ onye na-anabata ya, si otú ahụ na-egbochi nzaghachi nke PAF, si otú a na-arụ ọrụ nchebe obi. Nsonaazụ gosiri na rutin bụ onye na-anabata PAF.

Anti-nnukwu pancreatitis

Nnukwu Rutin ntụ ntụ nwere ike igbochi ọnọdụ hypocalcemia nke ọma ma belata mkpokọta Ca2 + na anụ ahụ pancreatic. Nnyocha achọpụtala na rutin nwere ike ịbawanye ọdịnaya nke phospholipase A2 (PLA2) na anụ ahụ pancreatic oke, na-atụ aro na rutin nwere ike inwe mmetụta mgbochi na ntọhapụ na ịgbalite PLA2 na anụ ahụ pancreatic; rutin nwere ike igbochi ihe omume hypocalcemia nke ọma na oke AP, nke nwere ike na-ebelata mmebi pathophysiological na AP site na igbochi nnabata Ca2 + na ibelata ibu Ca2 + na sel anụ ahụ pancreatic.

Kwalite ahụike obi

A bịa n'ihe gbasara ahụike obi, nchọpụta na-adịbeghị anya gosiri na Rutin ntụ ntụ na-enyere aka ịnọgide na-agbatị arịa ọbara, belata adịghị ike nke arịa ọbara, belata permeability nke capillary ma gbochie nsogbu sitere na ọbara mgbali elu.

Wepụ ihe mgbaàmà ogbu na nkwonkwo

Ọmụmụ anụmanụ na-egosi na ọgwụ antioxidant a nwere ikike igbochi mbufụt na-adịghị ala ala. Nke a na-eme ka ọ bụrụ ọgwụgwọ okike maka ọrịa ogbu na nkwonkwo. Ndị nchọpụta Russia achọpụtala na rutin nwere ike ibelata oke mmepụta nke radicals free na ọrịa ogbu na nkwonkwo. Ha kwubiri na enwere ike iwere ya dị ka onye na-ahụ maka enyemaka bara uru.

Gbochie ọrịa metabolic

Nnyocha na-egosi na rutin nwere ike ichebe anyị pụọ na mmetụta nke ọrịa metabolic ka anyị na-eme agadi. Nnyocha metụtara oke ndị merela agadi chọpụtara na flavonoids na-egbochi mmụba nke shuga ọbara na-ebu ọnụ, ọkwa insulin na ọbara mgbali.

Ọchịchị Rutin kwalitere ọrịa metabolic metụtara ịka nká na oke site n'ibelata mbufụt, mkpokọta lipid, nrụgide oxidative, na ọrịa mitochondrial, nke kpatara ọdịda mitochondrial dị na ihe fọrọ nke nta ka ọ bụrụ sel ọ bụla dị n'ahụ mmadụ.

Chebe ahụike ụbụrụ

Nnyocha na-egosi na rutin nwere mmetụta nchebe megide mmerụ ahụ ụbụrụ na mmerụ ahụ metụtara afọ. Ọ na-enyekwara aka ịkwalite ahụike ụbụrụ n'ihi ihe na-egbochi mkpali na ihe antioxidant.

Na 2018, nnyocha e bipụtara na Oxidative Medicine na Cellular Longevity gosiri na bioflavonoid a nwere ike ịbụ ihe na-ekwe nkwa neuroprotective ogige maka ọgwụgwọ nke ọrịa gụnyere Alzheimer's, Parkinson's na Huntington ọrịa neurodegenerative ọrịa. Ndị na-eme nchọpụta kwenyere na ọ na-echebe ahụike ụbụrụ site na ibelata cytokines pro-inflammatory, na-abawanye ọrụ enzyme antioxidant na iweghachi ọrụ nke mitochondrial complex enzymes n'ime sel.

Mee ka mmeghari ka mma

Na ọgwụ ọdịnala, a maara rutin maka ikike ya ime ka arịa ọbara sie ike ma melite mgbasa ọbara. A na-eji ya iji belata ọdịdị nke veins varicose, belata hemorrhoid yana gbochie ọrịa strok nke hemorrhagic nke veins ma ọ bụ akwara gbawara agbawa na-akpata.

Dị ka nnyocha e bipụtara na International Journal of Molecular Sciences si kwuo, a kọrọ na nkwadebe rutin na-ebelata nke ọma n'ọzịza ụkwụ, na-ebelata ihe mgbu ụkwụ, ma belata nkwụsị ụkwụ, ịdị arọ, na itching. Nke a nwere ike ịbụ n'ihi ikike ya ibelata mbufụt ma melite mgbasa ọbara.

Ntuziaka ngwa

1. Agba agba nri (dị ka lemon odo); antioxidant; ihe oriri na-edozi ahụ. A na-ejikarị eme ihe ọṅụṅụ oyi, ihe ọṅụṅụ, pastries, ngwaahịa anụ, ngwaahịa mmiri mmiri, wdg.

2. Vitamin ọgwụ. Ọ nwere mmetụta nke ibelata permeability capillary na fragility, na-edobe ma na-eweghachi elasticity nkịtị nke capillaries. A na-eji ya egbochi ma na-agwọ ọbara mgbali ọbara ọbara ọbara, ọbara ọgbụgba retina nke ọrịa mamịrị na hemorrhagic purpura. A na-ejikwa ya dị ka nri antioxidant na pigmenti.

3. Ọ nwere mmetụta mgbochi mkpali; vitamin P dị ka mmetụta, ọ nwere ike ịnọgide na-eguzogide arịa ọbara, belata permeability ya, belata fragility, wdg, ma nwee mmetụta na-ewepu lipid na imeju na-etinye abụba. Mmetụta iwepụ lipid na-apụta ìhè karịa mgbe ejikọtara ya na glutathione. ; Mmetụta antiviral na mgbochi nke aldose reductase.

Rutin ntụ ntụ soplaya

Yuantai Organic Bio na-agba mbọ inye ndị ahịa ihe kacha mma Nnukwu Rutin ntụ ntụ na ọrụ ka onye ọ bụla na-azụ ahịa nwee ike ịnụ ụtọ nri eke, ahụike yana oke mma. Ọ bụrụ na ị nwere ajụjụ ọ bụla ma ọ bụ mkpa gbasara ngwaahịa anyị, biko nweere onwe gị ịkpọtụrụ anyị, anyị ga-azaghachi gị ozugbo enwere ike.

Ngwugwu & Mbupu

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