Silk Fibroin ntụ ntụ

Aha ngwaahịa: Silk Peptide Powder; Fibroin
CAS: 96690-41-4
Akụkụ: Cocoon
Ọdịdị: ọcha ntụ ntụ
Ndụ nchekwa: ọnwa 24
Asambodo:ISO9001,ISO22000,Kosher,Halal,HACCP
Mbupu ọsọ: 1-3 ụbọchị
Nkwakọ ngwaahịa: 1kg / aluminom foil bag; 5kg / katọn; 25kg / cardboard drum (ma ọ bụ dị ka ndị ahịa chọrọ)

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Kedu ihe bụ Fibroin ntụ ntụ?

Silk Fibroin ntụ ntụ, nke a makwaara dị ka: fibroin silk. Fibroin silk bụ protein polymer fiber eke ekepụtara na silk. Ọdịnaya ya bụ ihe dịka 70% ruo 80% nke silk. O nwere ụdị amino acid 18, nke glycine, alanine na serine nwere ihe karịrị 80% nke mkpokọta. N'ime mbipụta a, anyị ga-ewebata gị ihe ngosi arụmọrụ nke silk protein na ngwa ọhụrụ ya n'ọhịa nke ihe eji eme ihe na ihe mara mma. 


Uzuzu protein silk bụ ihe dị mkpa sitere n'okike nke nwere ihe eji arụ ọrụ nke ọma, biocompatibility, biodegradability, na mfe mgbanwe kemịkalụ, na-eme ka ọ bụrụ ihe dị mkpa biomaterial na nyocha ọgwụ na-emegharị ahụ. N'ime afọ ndị na-adịbeghị anya, a na-eji ihe ndị na-emepụta ihe na-emepụta ihe na-adabere na fibroin silk na-edozi anụ ahụ na ọgwụ na-eme ka ọkpụkpụ dị ka ọkpụkpụ, akpụkpọ anụ, irighiri akwara, na agwaetiti pancreatic. 


Ọrụ nke silk fibroin ihe na-achịkwa ọrụ cell ejirila nke nta nke nta akọwapụta ma ghọọ nhazi nduzi ya na Ọ bụ ihe dị mkpa maka ịmepụta nhazi nke silk fibroin nke ọgwụ na-eme ka ngwa ngwa nke silk fibroin na-arụ ọrụ na nkà mmụta ọgwụ. Ebe ndị ọzọ etinyere ya gụnyere nri, ihe ịchọ mma na ubi ndị ọzọ.

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Ndị na-egosi protein silk:

Ihe ngosi nka: ① Ọdịdị: mmiri mmiri na-acha odo odo na-acha odo odo, enweghị isi ísì, na-adị mfe soluble na mmiri. ② mmeghachi omume Biuret dị mma. ③ pH uru 6 ~ 7. Ọdịnaya protein: >/14%. Amino acids: ụdị 17 na mkpokọta, nwere ihe karịrị 87mg kwa ml. Ọdịnaya ntu: ihe na-erughị 1%. ⑦ Mercury, arsenic na lead dị arọ n'okpuru 1ppm n'otu n'otu. ⑧Ngụkọta ọnụ ọgụgụ nke nje bacteria (iberibe/m1) ≤ 10.

Ndekọ ogo: Silk fibroin bụ protein a na-ewepụta na silk. Ọ nwere ezigbo bioacompatibility na enwere ike ịkwadebe ya n'ụdị ihe dị iche iche dị ka ihe nkiri, gels, na microcapsules. N'ihi ihe pụrụ iche nke anụ ahụ na kemịkal ya, a na-eji ihe ndị silk fibroin eme ihe ugbu a ka a mụọla ọtụtụ ebe n'ọhịa nke ihe ndị na-ahụ maka biomedical, dị ka ihe ndị na-anaghị emegharị ahụ, ihe ndị na-emepụta mkpụrụ ndụ cell, ndị na-ahapụ ọgwụ na-akwado, akụkụ ahụ arụrụ arụ, wdg.

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Uru nke Fibroin

1 Nrụzi anụ ahụ akwara

Ndozi trauma akwara bụ nnukwu nsogbu na ọgwụ taa. Ọrịa akwara na-adịghị ahụkebe nke kpatara trauma, ọrịa, wdg, na enweghị njupụta dị mkpa n'oge usoro mgbake ga-eduga n'ịmepụta neuromas. Ya mere, a ka na-ahụta ntụgharị autologous dị ka usoro nrụzi kacha dị irè ruo ugbu a. Ruo ogologo oge, n'ihi ụkọ ụkọ nke ndị na-enye onyinye na ọganihu ngwa ngwa na nyocha banyere ihe ndị ọzọ, ọnụ ọgụgụ buru ibu nke ndị ọrịa enwebeghị ike ịnweta ọgwụgwọ oge na nke dị irè. Ihe ndị na-abụghị akwara maka ịrụzi akwara gụnyere tubes silicone, akwara skeletal, akwara akwara ma ọ bụ venous ọbara, na chitin. Nnyocha e mere n'ime afọ iri gara aga egosila na ihe ndị na-arụzi akwara dị mma aghaghị izute ọnọdụ ndị a: Nke mbụ, onye na-anọchi ya aghaghị imebi kpamkpam, enweghị nsị anụ ahụ, ma nwee ike ịkwalite mmeghari nke mkpụrụ ndụ akwara. Ihe ndị na-adịghị emebi emebi kwesịrị iwepụ site na ịwa ahụ ma emechaa. Nke abụọ bụ na akwara akwara dị na onye nnata ruo ogologo oge iji mejuo axon emegharịrị site na anastomosis distal. Nke atọ, onye nọchiri anya nwere ohere zuru oke na oke elu iji zute uto nke mkpụrụ ndụ Schwann na njem nke nri.

2 mmezi akpụkpọ anụ

A na-ekewa akpụkpọ ahụ mmadụ na epidermis na dermis. Epidermis bụ oyi akwa kachasị elu nke akpụkpọ ahụ ma na-akpakọrịta na gburugburu mpụta. Ọ na-arụkarị ọrụ nchebe. E kewara epidermis site n'ime ime: oyi akwa basal cell, oyi akwa granular, oyi akwa cell doro anya na oyi akwa ọka. N'ọnọdụ nkịtị, oyi akwa basal cell na-aga n'ihu na-agbanwe agbanwe, na-apụ apụ, na-edochikwa mkpụrụ ndụ senescent mgbe niile na oyi akwa ọka. Enwere ike idozi ọnya obere mpaghara site na mmegharị nke mkpụrụ ndụ epidermal. Ọzọkwa, a na-etinye nyocha n'ahụ akpụkpọ ahụ site n'iji ike na-akpụ akpụ na ịrụzi mkpụrụ ndụ akpụkpọ ahụ n'ọrụ. Silk fibroin akpụkpọ anụ ọ bụghị naanị nwere ezigbo mmiri na ikuku permeability, kamakwa ọ nwere ike adhesion na ọnya elu na-enweghị ogide ohere (ya bụ, ọ dịghị emetụta uto nke autologous akpụkpọ n'okpuru wuru akpụkpọ mkpuchi). Ọ naghị abanye na nje bacteria na ọ naghị ekpuchi ya na mmiri. Ọ dị nro ma na-arapara nke ọma na ọnya ahụ. Tụkwasị na nke ahụ, akpụkpọ anụ silk fibroin dị nro, dị nro na nke na-adịghị ewe iwe, ya mere ọ bụ ihe dị mma maka akpụkpọ anụ artificial na mkpuchi ọnya.

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3 Biotechnology


N'ihe gbasara nkà na ụzụ biotechnology, a pụrụ iji akpụkpọ anụ silk fibroin dị ka ndị na-ebu maka enzymes na-adịghị agbanwe agbanwe na maka nkwadebe nke biosensors. Silk Fibroin ntụ ntụ bụ protein polymer sitere n'okike nke nwere usoro mkpụrụ ndụ pụrụ iche, akụrụngwa akụrụngwa mara mma, nnabata mmiri dị mma na ihe nchekwa ọkụ, yana ihe mgbochi nje. Ọ bụ ezigbo ihe na-ebu ihe na-ebugharị enzyme maka ngwa ahụike na biochemical. , gbaa ụka na chemical analysis na ndị ọzọ ubi.

4 ịchọ mma


N'oge usoro Ming, Li Shizhen dekọrọ na nkà mmụta ahụike ya "Compendium of Materia Medica": silk eke nwere ike ime ka akpụkpọ ahụ mara mma, wepụ ntụpọ ojii, ma nwee ike ịgwọ ọrịa akpụkpọ anụ. N'ihe gbasara ihe ịchọ mma, protein silk na-abịakarị n'ụdị abụọ: ntụ ntụ silk fibroin na peptide silk. Silk fibroin ntụ ntụ ọ bụghị nanị na ọ nwere ihe dị nro dị nro pụrụ iche nke protein silk na ọrụ nke ịmịkọrọ ụzarị ultraviolet na iguzogide radieshon anyanwụ, ma ọ dịkwa mma, dị nro, nwere ezigbo ikuku ikuku na nrapado siri ike. Ọ nwere ike ịmịnye ma hapụ mmiri na mgbanwe na okpomọkụ gburugburu ebe obibi na iru mmiri, nke dị mma maka stratum corneum nke akpụkpọ ahụ. Mmiri nwere mmetụta njide ka mma. Ya mere, silk fibroin ntụ ntụ bụ ihe magburu onwe isi ihe na ihe ịchọ mma mara mma. peptide silk nwere mmetụta moisturize dị mma; ọ nwere ike permeability, nwere ike banye na stratum corneum na ikpokọta na epithelial sel, na-ekere òkè na melite metabolism nke epithelial sel, na-edozi mkpụrụ ndụ, na-eme ka akpụkpọ ahụ dị nro, dị nro, na-agbanwe ma na-egbuke egbuke; ọ nwere ezigbo ihe mejupụtara O nwere ihe nkiri ihe nkiri ma nwee ike ịmepụta ihe nkiri nchebe n'elu akpụkpọ anụ na ntutu. Ihe nkiri a nwere ezigbo mgbanwe na elasticity; ọ bụ mgbochi ultraviolet radieshon. Tyrosine na silk fibroin peptide na-emeghachi omume na fotochemically na ụzarị ultraviolet, nke nwere ike igbochi ma belata radieshon ultraviolet. Mmebi nke ahụ mmadụ; na-egbochi mmepụta nke melanin na akpụkpọ ahụ, silk peptide protein nwere mmetụta nke igbochi ọrụ tyrosinase, si otú ahụ na-egbochi mmepụta nke melanin.

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5 Ọrụ nri na ahụike

5.1 belata agụụ ma chebe imeju


N'afọ ndị na-adịbeghị anya, a na-eji fibroin silk na-eme ka ihe oriri na-edozi ahụ na-echebe ya na imeju ya. Tussah silk fibroin mgbochi hangover na imeju na-echebe nri na-arụ ọrụ sitere na tussah silk fibroin nanopowder na ọgwụ ndị China ọdịnala maka ọgwụ na nri nri dị ka akụrụngwa, a na-anụcha ya site na iji nanotechnology. Ọ nwere ike ichebe ahụ mmadụ nke ọma ma belata mmebi mmanya.

5.2 Mbelata shuga ọbara


N'oge a, enwere ọtụtụ ọgwụ hypoglycemic dị ka sulfonylureas, biguanides, na thiazolidinediones. Otú ọ dị, iji ọgwụ ndị a eme ihe ogologo oge nwere ike inwe mmetụta dị njọ na-egbu egbu na mmetụta. Dochie ọgwụ ndị a dị n'Ebe Ọdịda Anyanwụ na ọgwụ ndị dị irè, ndị na-adịghị egbu egbu na ndị na-enwe mmetụta dị n'akụkụ iji gwọọ ọrịa shuga ga-abụ nnukwu uru nye ndị ọrịa na-arịa ọrịa shuga. Ọnụ ọgụgụ dị ukwuu nke ọmụmụ na nkà mmụta ọgwụ egosilarị na ndị na-egbochi α-glucosidase nwere ike igbochi ma gwọọ ọrịa shuga.

5.3 Ọrụ ndị ọzọ


Dị ka ihe mejupụtara amino acid nke Bombyx mori silk fibroin si kwuo, a pụrụ ịhụ na fibroin silk nwere tyrosine. Enwere ike ịtụgharị Tyrosine ka ọ bụrụ dopamine mgbe usoro ụfọdụ gasịrị. Dopamine nwere ike igbochi nchịkwa akwara na sistemu ụjọ nke etiti. Enweghị Dopamine nwere ike ibute ọrịa Parkinson. Maka ndị ọrịa nwere ọrịa Parkinson, iri ntụ ntụ silk fibroin nwere ike ịgbakwunye tyrosine ma gbochie ma gwọọ ọrịa Parkinson nke ọma.


Njirimara nlekọta anụ ahụ nke protein silk gụnyere ihe ndị a:


1. Ọ nwere ọrụ nke na-eme ka mmiri na-edozi ahụ na-edozi ahụ.


Silk Fibroin ntụ ntụ nwere ezigbo mmiri absorption na ntọhapụ Njirimara. Ọdịdị molekụla ya nwere ọtụtụ mkpụrụ ndụ ihe nketa hydrophilic n'elu ihe nhazi akụkụ atọ nke molekụla. Ihe owuwu a na-egosi na protein silk bụ ihe na-achịkwa iru mmiri sitere n'okike ma nwee mmetụta dị mma nke mmiri mmiri.


Nnwale na-egosi na na okpomọkụ nke 27 Celsius C, iru mmiri dị 86% RH, na oge mmịnye mmiri nke awa 12, ọnụego mmịnye mmiri nke ngwọta fibroin 2.5% bụ nha nha nha mmiri nke 48% glycerol. Ya bụ, ịgbakwụnye obere ngwọta protein silk na ihe ịchọ mma nwere ike nweta ezigbo moisturizing na hygroscopic Njirimara. Ka ọ dị ugbu a, ihe ịchọ mma nwere protein silk dị ka ihe mgbakwunye bụ isi dị n'ahịa, dị ka mmiri mmiri, ihe na-ehicha ihu, ihe nchacha ihu, mmiri ịsa ahụ, wdg.


2. Ọ nwere mmetụta nke igbochi mmepụta nke melanin akpụkpọ.


Nnyocha achọpụtala na Fibroin ntụ ntụ nwere ihe onwunwe nke igbochi ọrụ tyrosinase. N'ihi na ọnụ ọgụgụ dị elu nke hydroxyl amino acids dị na protein silk bụ ihe mgbagwoju anya dị ka ọla kọpa na ígwè, ọ na-emetụta ọrụ nkịtị nke tyrosinase.


Ọ bụrụ na ị na-etinye ihe ịchọ mma nwere protein silk mgbe niile na akpụkpọ gị, ọ nwere ike igbochi mmepụta nke melanin nke ọma na akpụkpọ ahụ ma mee ka akpụkpọ ahụ dị ọcha ma dị nro. Tyrosine, tryptophan, phenylalanine, wdg na protein silk nwere ike ịmịkọrọ ụzarị ultraviolet nke ọma.


3. Kwalite mmegharị anụ ahụ ma gbochie mmebi kemịkal


Protein silk na-arụ ọrụ nke ọma n'ịkwalite ọgwụgwọ ọnya anụ ahụ. Protein silk adịghị ewe iwe ma na-eme ka ọnya gwọọ ngwa ngwa. Ihe ịchọ mma nwere protein silk na-arụkwa ọrụ nke ọma n'igbochi mgbaka akpụkpọ ahụ. N'otu oge ahụ, protein silk nwekwara ike iguzogide mmebi nke akpụkpọ ahụ site na kemịkalụ dị ka ìhè anyanwụ, microwaves, acids na alkalis, na mmetọ ikuku. Ọ nwere ike igbochi ọgbọ nke ụdị oxygen na-emeghachi omume ma gbochie wrinkles akpụkpọ na ịka nká.


4. Fibroin nwekwara ọrụ antioxidant


Melalton, nke chlorinated na-eji oxygen na-arụ ọrụ, nwere uru ahụike dị mkpa n'ịgwọ ọrịa ndị a na-ahụkarị dị ka kansa, arteriosclerosis, na ọrịa shuga, ma ọ bụ n'ichekwa akpụkpọ ahụ. Nsonaazụ nnwale na-egosi na a na-eme ka lipids oxidized na 37 Celsius C maka nkeji 120, a tụrụ nsonaazụ oxidation mgbe ị na-agbakwunye protein silk ma ọ bụ BSA. Uru njikwa nke ego oxidation bụ 100%, gosipụtara dị ka ọnụ ahịa ikwu.


Ka ọnụọgụ Fibroin eke eke na-abawanye, lipids oxidized na-ebelata, na-ekwenye na protein silk nwere ikike antioxidant, yana na protein silk dị irè karịa vitamin C, nke nwere ọrụ antioxidant.

Isi ihe ngosi:


item

Silk fibroin ntụ ntụ

e ji mara

ntụ ntụ edo edo ọcha ma ọ bụ isi awọ

Ngụkọta nitrogen(%)

≥14.5

Mfu na ihicha(%)

≤6.0

Ihe fọdụrụ na ọkụ (%)

≤4.0

PH

5.0-7.0

Pb/ (mg/kg)

≤5

Dị ka (mg/kg)

≤1

Hg (mg/kg)

≤0.1

Mkpokọta Ọnụ Ọgụgụ (CFU/g)

≤1000

E.Coli(MPN)(100g)

≤90

Salmonella, Staphylococcus

-adịghị mma



Asambodo

Yuantai Organic Bio na-agba mbọ inye ndị ahịa ihe kacha mma Nnukwu silk fibroin dị ọcha na ọrụ ka onye ọ bụla na-azụ ahịa nwee ike ịnụ ụtọ nri eke, ahụike yana oke mma. Ọ bụrụ na ị nwere ajụjụ ọ bụla ma ọ bụ mkpa gbasara ngwaahịa anyị, biko nweere onwe gị ịkpọtụrụ anyị, anyị ga-azaghachi gị ozugbo enwere ike.

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Ngwugwu & Mbupu

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Ụlọ ọrụ anyị na ụlọ ọrụ mmepụta ihe

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