Ectoin ntụ ntụ

Kedu ihe bụ Ectoin ntụ ntụ?

Ectoin ntụ ntụ: nke a makwaara dị ka tetrahydropyrimidine carboxylic acid, 2-methyl-1,4,5,6, -tetrahydropyrimidine-4-carboxylic acid, carboxymethyl dextran, bụ ihe amino acid pụrụ iche na-adịkarị na ụfọdụ microorganisms pụrụ iche na osisi. Ọ nwere ihe nchebe pụrụ iche nke nwere ike ichebe sel nke ọma site na nrụgide gburugburu ebe obibi dị iche iche, dị ka ụzarị ultraviolet, nkụ, elu na obere okpomọkụ, wdg.

N'afọ 1985, Prọfesọ Galinski chọpụtara n'ọzara Egypt na nje bacteria halophilic ọzara na-emepụta ihe nchebe sitere n'okike - Ectoin - n'ime mpụta nke mkpụrụ ndụ dị n'okpuru oke okpomọkụ, nkụ, ọkụ ọkụ UV, na gburugburu salinity dị elu. Nke a na-eme ka ọrụ nrụzi onwe ya rụọ ọrụ. Na mgbakwunye na ọzara, a na-ahụkwa ero a n'ala saline-alkali, ọdọ mmiri nnu, na mmiri oké osimiri.

Ọdịdị nke YTBIO bụ cyclic amino acid ewepụtara, nke carbonyl na nitrogen atom bụ polar ma nwee ezigbo hydrophilicity, ma bụrụkwa ndị na-anabata njikọ hydrogen na ndị na-enye onyinye, na-eme ka ọ bụrụ njikọ hydrogen kwụsiri ike na ụmụ irighiri mmiri iji mee ka mmịnye mmiri dịkwuo elu. Ke adianade do, ọ ga-etolite a pụrụ nnọọ iche mụ Ọdịdị na mmiri ụmụ irighiri ihe n'okpuru omume nke van der Waals agha, wdg, si otú na-enye Ectoin a pụrụ iche nchebe mmetụta, nke nwere ike hazie na ikpokọta na gburugburu mmiri ụmụ irighiri ihe na amino acid mmepụta iji mepụta. ihe a na-akpọ "Ectoin hydropower". Ngwakọta." Mgbagwoju anya gbara gburugburu sel, enzymes, protein na biomolecules ndị ọzọ, na-eme ka akpụkpọ ahụ hydration kwụsiri ike na gburugburu ha iji nọgide na-enwe nguzozi nrụgide osmotic ma zere ikpochapụ oke mmiri nke intracellular.

Mmetụta na mmetụta nke ectoin

1. Antioxidant ma chebe mkpụrụ ndụ site na mmebi

Ectoine na-arụ ọrụ nke ọma nwere ike ịchụpụ radicals efu, gbochie peroxidation lipid, ma chebe akpụkpọ ahụ pụọ na mmetọ gburugburu ebe obibi na mmebi radieshon ultraviolet. Mmetụta nchebe nke ectoin na sel na-eme ka ụmụ irighiri mmiri na-ejikọta nke ọma n'akụkụ akpụkpọ ahụ iji mepụta mgbagwoju anya na nchebe. A na-ebelata mmetụta nke mmetọ mpụga na sel site na nkwụsi ike nke Ectoin. Na-echebe mkpụrụ ndụ site na mbufụt nke ihe nrụgide gburugburu ebe obibi dị ka akpịrị ịkpọ nkụ, UV radieshon, esemokwu, ma ọ bụ ụmụ irighiri ikuku.

2. Mma akpụkpọ mmiri itule foto

Ectoin nwere ike jikọta ya na ụmụ irighiri mmiri dị na anụ ahụ. Site na nguzobe nke mmiri Ectoin, ọnụ ọgụgụ ụmụ irighiri mmiri na-abawanye na mmekọrịta hydrophobic na-abawanye, si otú ahụ na-eme ka nkwụsi ike nke protein ahụ dịkwuo elu. Na-enyere aka igbachi akpụkpọ ahụ na mmiri ma zere mmiri ozuzo, nke na-eme ka akpụkpọ ahụ dịkwuo mma ma na-agbakọta.

3. Dozie ihe mgbochi akpụkpọ ahụ ma na-emeso foto dermatitis

Mmetụta nke iji usoro dị iche iche nwere ectoine na ọnwụ mmiri transepidermal (TEWL). Ihe karịrị ihe ọmụmụ iri asaa. N'ihi ojiji nke Ectoin ude. A na-ebelata oke mmiri nke transepidermal na ndị ọrịa nwere akpụkpọ anụ ahụ na anụ ahụ atopic. Ectoin nwere ike ịkwalite nhazi keratin, nyere aka rụkwaa ihe mgbochi akpụkpọ ahụ, ma mee ka akpụkpọ ahụ dịkwuo mma.

Ọmụmụ ihe a na-eche na ectoine dị n'elu ga-aba uru na ndị ọrịa nwere atopic dermatitis (AD). N'ime usoro, n'otu n'otu, kpuru ìsì abụọ, multicenter, a na-enyocha ịdị irè nke ude nwere ectoine (EHK02-01) na ọgwụgwọ nke ndị ọrịa 65 nwere AD dị nwayọọ ma dị oke ala. Atụnyere ịdị irè ya na ude mgbochi mkpali na-adịghị steroidal gara aga hụrụ na ọ na-eme ihe bụ isi na ọrụ mgbochi anụ ahụ ya mere nwere ụdị omume ahụ. Kọwaa na enwere ike iji ectoin gwọọ dermatitis.

4. Mee ka akpụkpọ ahụ dịkwuo mma

Ectoin na-abawanye mmịkọ mkpụrụ ndụ n'ime nzaghachi maka ọnọdụ dị oke egwu, dị ka oke okpomọkụ ma ọ bụ nrụgide osmotic. A na-ewepụ Ectoin na oyi akwa hydration n'elu akpụkpọ ahụ ma ọ dịghị emetụta mmetụta nke akpụkpọ ahụ. Tụkwasị na nke ahụ, n'ihi na ectoin na-eme ka mmiri dị n'elu cell dịkwuo mma, na-eme ka anya dị n'etiti ụmụ irighiri ihe, ma na-eme ka mmiri dị n'etiti ndị isi lipid dị na akpụkpọ ahụ cell, si otú ahụ na-eme ka akpụkpọ ahụ dịkwuo mma.

5. Meziwanye microenvironment akpụkpọ anụ ma gbochie mbufụt

Usoro SDS-patch kpaliri Erythema n'ihu ndị ọrụ afọ ofufo 20 wee tụọ ya n'ụzọ dị iche iche. Mgbe nlebachara nke mbụ (0), a na-etinye ngwaahịa nnwale ahụ n'otu n'otu n'ihu ogwe aka ugboro abụọ n'ụbọchị maka ụbọchị 7, na-ahapụ otu mpaghara n'enweghị ọgwụgwọ dịka njikwa. Eserese ahụ na-egosi oke erythema n'ihe metụtara uru mmalite (t0). Mgbe ụbọchị 7 gachara ọgwụgwọ na 4% Ectoin ude, erythema belatara site na 23%.

Ectoin na-achịkwa microenvironment akpụkpọ ahụ, na-egbochi mmepụta nke ndị mgbasa ozi mkpali, na-ebelata mmeghachi omume mkpali, na-eme ka akpụkpọ ahụ dị nro dị jụụ.

6. Mgbochi glycation na mgbochi wrinkle

Mgbe izu anọ nke ọgwụgwọ Ectoin gachara, olu wrinkle na-akawanye mma site na 4%, akpịrịkpa akpụkpọ ahụ belatara site na 23%, na isi ike na-abawanye site na 76%. Tupu (aka ekpe) na mgbe (n'aka nri) ọgwụgwọ na Product B (verum na 52% Ectoin) maka izu 2, a na-atụle elu akpụkpọ ahụ site na iji usoro SELS (Visioscan), ma mee ka elu akpụkpọ ahụ dịkwuo mma. Ectoin nwere ike igbochi mmepụta nke ngwaahịa njedebe glycation ma na-egbu oge usoro glycation nke akpụkpọ ahụ, si otú ahụ nweta mmetụta mgbochi wrinkle na ime ka akpụkpọ ahụ dịkwuo nro, dị nro na nke siri ike.

YTBIO Ectoin ntụ ntụ na-arụkwa ma na-echebe akpụkpọ ahụ, onye na-azọpụta akpụkpọ anụ

Ectoin nwere ike ichebe mkpụrụ ndụ Langerhans nke ọma (Mkpụrụ ndụ Langhans dị mkpa na-alụso ọrịa ọgụ na akpụkpọ ahụ, nke dị n'etiti keratinocytes na akpụkpọ anụ epidermal, na-echebe akpụkpọ ahụ megide microorganisms, ụzarị ultraviolet, allergens, wdg) site na mkpali mpụga. , si otú ahụ na-eme ka mgbochi akpụkpọ ahụ dịkwuo elu ma na-enye ndị mmadụ iwu akpụkpọ ahụ siri ike. Ndị ọkà mmụta sayensị mere nnwale na mkpụrụ ndụ Granhans. Nnwale na-egosi na ngwaahịa ndị na-eji Ectoin nwere mmetụta nchebe dị ukwuu na mkpụrụ ndụ Langerhans. 0.5% Ectoin nwere ike chebe mkpụrụ ndụ Langerhans kpamkpam na akpụkpọ ahụ nke ekpughere na radieshon UV.

Ectoin nwere ike imeziwanye nchebe nke mkpụrụ ndụ akpụkpọ ahụ nke ọma, na-abawanye ọrụ nrụzi akpụkpọ ahụ nke mkpụrụ ndụ, ma mee ka akpụkpọ ahụ nwee ike iguzogide mwakpo nke microorganisms na allergens nke ọma.

Ecodoin nwekwara ike ichebe DNA nke mkpụrụ ndụ akpụkpọ ahụ mmadụ site na radieshon UV-A ma zere nkwụsịtụ nke yinye DNA nke ionizing radieshon electron kpatara.

N'ihe gbasara ịlụ ọgụ megide ụzarị ultraviolet, Ectoin nwere ike igbochi mmebi DNA cell nke band UVA kpatara, ogologo ogologo ogologo ogologo na ụzarị ultraviolet, si otú ahụ nweta mmetụta nchebe nke nchebe anyanwụ na mgbochi foto. Nsonaazụ ule gosiri na ectoin nwere ike mezie mmebi cell nke UV kpatara. 0.5% ectoin na-eweghachi ọrụ cell na 86%, na 3% ectoin nwere ike iwepụ mmebi nke UV kpatara na sel.

Banyere nka nka nke Ectoin

Ka ọ dị ugbu a, a na-ewepụta Ectoin n'ụzọ bụ isi n'ụdị halophile. Emebela teknụzụ ụlọ ọrụ nke iji halobacteria na-emepụta ectoine. Nkà na ụzụ a na-eji glycerol dị elu dị ka isi iyi carbon ma na-eji usoro emepụtara nke a na-akpọ "mmiri ara ehi nje".

Ụdị Halobacteria na-eto ma na-amụba na ngwọta omenala nnu dị elu (dị ka 100g/L). Dịka solute nkwụghachi ụgwọ nrụgide osmotic, ectoine na-agbakọta n'ọtụtụ buru ibu na ụfọdụ nje bacteria halophilic iji guzogide nrụgide osmotic dị elu nke gburugburu mpụga. Mgbanwe; mgbe ntinye uche nke cell rutere n'ogo kachasị elu, ntinye nnu na-adaba na mberede site na nnukwu ntinye uche (dị ka 100g / L) na obere ntinye uche (dị ka 20g / L). Mgbe hypotonicity kpaliri, nje bacteria nwere ike hapụ nnu kwakọbara n'ime ụwa ozugbo. Ectoine dị n'ime sel iji zere mgbasawanye cell ma ọ bụ mmebi n'ihi mbelata nrụgide osmotic gburugburu ebe obibi. N'ikpeazụ, e nwere ike sachaa ectoine site na nzacha, crystallization na teknụzụ ndị ọzọ iji nweta ectoine.

Ectoin ntụ ntụ Supplier

Yuantai Organic Bio na-agba mbọ inye ndị ahịa ihe dị ọcha kacha mma Ectoin ntụ ntụ nnukwu ngwaahịa na ọrụ ka onye ọ bụla na-azụ ahịa nwee ike ịnụ ụtọ nri eke, ahụike yana oke mma. Ọ bụrụ na ị nwere ajụjụ ọ bụla ma ọ bụ mkpa gbasara ngwaahịa anyị, biko nweere onwe gị ịkpọtụrụ anyị, anyị ga-azaghachi gị ozugbo enwere ike.

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