Acetyl tetrapeptide-3 ntụ ntụ

Nkọwa: 99%
Usoro nchọpụta: HPLC
Ịrụ ọrụ: Nyere aka ito eto ntutu
Mbupu ọsọ: 1-3 ụbọchị
Ngwaahịa: Ọ dị na ngwaahịa
Asambodo: HACCP, HALAL, KOSHER, ISO9001, ISO22000, FDA
MOQ: 25KG
Ngwugwu: 25kg / gbọmgbọm
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Kedu ihe bụ Acetyl tetrapeptide-3?

Acetyl tetrapeptide-3 ntụ ntụ bụ peptide biomimetic nke mejupụtara amino acid anọ nwere ike iṅomi mmetụta nke peptides eke na ahụ mmadụ, na-akpali akpali cell proliferation na ịchịkwa cell iche iche, na-ekere òkè na intercellular nkwurịta okwu na-akpali follicle mmepe ntutu isi. N'otu oge ahụ, acetyl tetrapeptide-3 nwere ike mee ka e guzobe protein matriks extracorporeal (ECM), dị ka adhesin, collagen III na VII, wdg, si otú ahụ na-emeziwanye usoro nke ntutu isi n'ụzọ dị irè ma na-abawanye nkwụsi ike nke nkwụsị ntutu. Ebe ọ bụ na acetyl tetrapeptide-3 bụ peptide nke sitere na amino acids, ọ gaghị enwe mmetụta ọ bụla mgbe ejiri ya mee ihe n'ime ahụ mmadụ ruo ogologo oge, ọ dịkwa mma maka ọgwụgwọ ogologo oge nke ntutu isi. N'okwu, acetyl tetrapeptide-3 bụ akụrụngwa akụrụngwa nke nwere ike igbochi ntutu isi ma kwalite uto ntutu.

Acetyl tetrapeptide-3 nwere ike mee ngwangwa guzobe protein extracorporeal matrix (ECM), dị ka adhesin, collagen III na VII, wdg, si otú ahụ na-emeziwanye usoro nke ntutu isi nke ọma ma na-abawanye nkwụsi ike nke ntutu ntutu. Ebe ọ bụ na acetyl tetrapeptide-3 bụ peptide nke sitere na amino acids, ọ gaghị enwe mmetụta ọ bụla mgbe ejiri ya mee ihe na ahụ mmadụ ruo ogologo oge, ọ dịkwa mma maka ọgwụgwọ ogologo oge nke ntutu isi.

Olee uru?

Acetyl tetrapeptide-3 enweghị ike ibelata DHT ozugbo, mana ọ nwere ike ịkwalite nguzogide ntutu isi na DHT. Ọ nwere ike kpalie papilla ntutu ma mee ka njikọ protein ECM dịkwuo elu, na-abawanye olu nke ntutu isi; na-arụkwa anụ ahụ epidermal-dermal junction (DEJ), na-akwalite nhazi nke ntutu isi na ntutu isi, na-akpali akpali uto ntutu; ọ nwekwara ike ibelata ntutu isi nke ọma n'ihi ịka nká. Na-eme ka ntutu dị ogologo, eke, dị nro na nke siri ike. N'otu oge ahụ, acetyl tetrapeptide-3 nwere ike imekọ ihe na akụrụngwa ndị ọzọ na-egbochi 5a-reductase iji gbochie ntutu isi na ntutu isi, na-enweta mmetụta nke 1 + 1> 2.


Iji gosi mmetụta nke acetyl tetrapeptide-3 na igbochi ntutu isi, ndị nchọpụta mere 5 in vitro na in vivo.


01 Synthesis nke collagen

Ndị na-edozi collagen dị ka protein adhesion, collagen III na VII, wdg, nwere ike ime ka protein ECM ghara ịdị irè, si otú ahụ na-edozi ntutu isi nke ọma. Collagen nwere amino acid abụọ akọwapụtara: hydroxylysine na hydroxyproline. A na-ejikọta ọdịnaya Hydroxyproline nke ọma na mmepụta collagen. Mkpụrụ ndụ papilla dermal na-emepụta protein na collagen dị ka fibroblasts akpụkpọ ahụ. Site n'ịtụle ọdịnaya hydroxyproline nke fibroblasts mmadụ na-emepụta na / na-enweghị mgbakwunye nke acetyl tetrapeptide-3, mmetụta nke acetyl tetrapeptide-3 na Mmetụta na nchịkọta collagen.


Ihe omuma a gosiputara na sel ejiri acetyl tetrapeptide-3 gosiputara oke hydroxyproline, na-egosi n'uzo di iche na acetyl tetrapeptide-3 na-akpali mmepụta nke collagen ma pụtakwara na ogige ahụ na-akpali dermal papilla collagen. nke ọgbọ.

Acetyl tetrapeptide-3

Ọgụgụ 10. Hydroxyproline ọdịnaya na fibroblasts


02Mkpalite njikọ protein ECM

Iji gosi mmetụta nke acetyl tetrapeptide-3 na protein ECM, ndị nchọpụta jiri nhọrọ immunofluorescence tụnyere fibroblasts iji / na-enweghị acetyl tetrapeptide-3 iji hụ njikọ nke protein ECM. Immunofluorescence bụ usoro na-eji fluorescent agents na-enye nleba anya nke ukwuu nke akụkụ cellular, dị ka protein fluorescent zuru ụwa ọnụ - GFP - jikọtara na protein ezubere iche.


Data na-egosi na acetyl tetrapeptide-3 nwere ike kpalite njikọ nke protein ECM dị ka laminin na collagen III, na-abawanye ọdịnaya laminin na ọdịnaya collagen III site na 65% na 285% n'otu n'otu, na-akpali akpali nhazigharị akpụkpọ ahụ. , na-eme ka ntutu isi na-ebuwanye ibu.

Acetyl tetrapeptide-3 ntụ ntụ

Ọgụgụ 11. Mkpali nke njikọ protein ECM site na fibroblasts


03 isi ihe

Ndị na-eme nchọpụta kewapụrụ ntutu isi mmadụ dị mma na akpụkpọ anụ ahụ mmadụ site na microdissection wee zụlite ha na mgbasa ozi omenala na ma ọ bụ na-enweghị 0.0006% acetyl tetrapeptide-3 maka ụbọchị 8 iji tụọ acetyl tetrapeptide-3. Mmetụta na-eto eto nke ntutu isi na ntutu isi mmadụ.


Nsonaazụ gosiri na mgbe ụbọchị 8 gachara, ma e jiri ya tụnyere ntutu isi a na-adịghị edozi ya, ogologo ntutu isi nke a na-eji acetyl tetrapeptide-3 mụbara site na 35%, na-egosi na acetyl tetrapeptide-3 nwere ike ịkpali uto ntutu mmadụ.

Acetyl tetrapeptide-3 ntụ ntụ

Ọgụgụ 12. Ntụle ogologo ntutu isi


A na-ekewapụ ntutu isi mmadụ dị mma na dermis-subcutaneous abụba interface nke akpụkpọ anụ isi mmadụ site na microdissection, na omenala omenala gbakwunyere na acetyltetrapeptide-3 na minoxidil maka ụbọchị 7, na-eji micrometer kwa awa 24 ọ bụla. Kpochie oghere ntutu abụọ ahụ n'okpuru microscope iji tụọ anya n'ogo n'ogo ntutu ntutu. Data na-egosi na acetyl tetrapeptide-3 nwere ike ime ka ntutu mmadụ na-eto nke ọma, na uto dị elu karịa nke minoxidil.

Acetyl tetrapeptide-3 ntụ ntụ

Ọgụgụ 13. Ọnụ ọgụgụ ntutu isi nke minoxidil na acetyltetrapeptide-3

Acetyl tetrapeptide-3 na-ebu

Yuantai Organic Bio na-agba mbọ inye ndị ahịa ihe kacha mma nnukwu acetyl tetrapeptide-3 ntụ ntụ na ọrụ ka onye ọ bụla na-azụ ahịa nwee ike ịnụ ụtọ nri eke, ahụike yana oke mma. Ọ bụrụ na ị nwere ajụjụ ọ bụla ma ọ bụ mkpa gbasara ngwaahịa anyị, biko nweere onwe gị ịkpọtụrụ anyị, anyị ga-azaghachi gị ozugbo enwere ike.

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